Failing stentless Bioprostheses in patients with carcinoid heart valve disease
Standard
Failing stentless Bioprostheses in patients with carcinoid heart valve disease. / Schaefer, Andreas; Sill, Bjoern; Schoenebeck, Jeannette; Schneeberger, Yvonne; Reichenspurner, Hermann; Gulbins, Helmut.
In: J CARDIOTHORAC SURG, Vol. 10, 27.03.2015, p. 41.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Failing stentless Bioprostheses in patients with carcinoid heart valve disease
AU - Schaefer, Andreas
AU - Sill, Bjoern
AU - Schoenebeck, Jeannette
AU - Schneeberger, Yvonne
AU - Reichenspurner, Hermann
AU - Gulbins, Helmut
PY - 2015/3/27
Y1 - 2015/3/27
N2 - BACKGROUND: Carcinoid tumor with consecutive endocardial fibroelastosis of the right heart, known as carcinoid heart valve disease (CHVD) or Hedinger's syndrome, is accompanied by combined right-sided valvular dysfunction with regurgitation and stenosis of the affected valves. Cardiac surgery with replacement of the tricuspid and/or pulmonary valve is an established therapeutic option for patients with Hedinger's syndrome. Little is known about the long term outcome and the choice of prosthesis for the pulmonal position is still a matter of debate.METHODS: The authors report three cases of pulmonary valve replacement with stentless bioprostheses (Medtronic Freestyle, Medtronic PLC, Minneapolis, MN, USA) due to severe pulmonary valve degeneration in consequence of Hedinger's syndrome.RESULTS: All patients presented with re-stenosis of the pulmonal valve conduit at the height of the anastomoses in a premature fashion. Due to the increased risk for repeat surgical valve replacement, two patients were treated by transcatheter heart valves.CONCLUSION: We do not recommend the replacement of the pulmonary valve with stentless bioprostheses in patients with CHVD. These valves presented with an extreme premature degeneration and consecutive re-stenosis and heart failure.
AB - BACKGROUND: Carcinoid tumor with consecutive endocardial fibroelastosis of the right heart, known as carcinoid heart valve disease (CHVD) or Hedinger's syndrome, is accompanied by combined right-sided valvular dysfunction with regurgitation and stenosis of the affected valves. Cardiac surgery with replacement of the tricuspid and/or pulmonary valve is an established therapeutic option for patients with Hedinger's syndrome. Little is known about the long term outcome and the choice of prosthesis for the pulmonal position is still a matter of debate.METHODS: The authors report three cases of pulmonary valve replacement with stentless bioprostheses (Medtronic Freestyle, Medtronic PLC, Minneapolis, MN, USA) due to severe pulmonary valve degeneration in consequence of Hedinger's syndrome.RESULTS: All patients presented with re-stenosis of the pulmonal valve conduit at the height of the anastomoses in a premature fashion. Due to the increased risk for repeat surgical valve replacement, two patients were treated by transcatheter heart valves.CONCLUSION: We do not recommend the replacement of the pulmonary valve with stentless bioprostheses in patients with CHVD. These valves presented with an extreme premature degeneration and consecutive re-stenosis and heart failure.
KW - Adult
KW - Bioprosthesis
KW - Carcinoid Heart Disease/complications
KW - Female
KW - Heart Valve Prosthesis
KW - Heart Valve Prosthesis Implantation/instrumentation
KW - Humans
KW - Male
KW - Middle Aged
KW - Pulmonary Valve Insufficiency/etiology
KW - Pulmonary Valve Stenosis/etiology
KW - Recurrence
KW - Reoperation
U2 - 10.1186/s13019-015-0238-5
DO - 10.1186/s13019-015-0238-5
M3 - SCORING: Journal article
C2 - 25880286
VL - 10
SP - 41
JO - J CARDIOTHORAC SURG
JF - J CARDIOTHORAC SURG
SN - 1749-8090
ER -
