Research ExplorerPublicationsExtravascular lung water and its association with weight, he...

Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients

Standard

Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients. / Huber, Wolfgang; Mair, Sebastian; Götz, Simon Q; Tschirdewahn, Julia; Siegel, Johanna; Schmid, Roland M; Saugel, Bernd.

In: INTENS CARE MED, Vol. 39, No. 1, 01.01.2013, p. 146-50.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Huber, W, Mair, S, Götz, SQ, Tschirdewahn, J, Siegel, J, Schmid, RM & Saugel, B 2013, 'Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients', INTENS CARE MED, vol. 39, no. 1, pp. 146-50. https://doi.org/10.1007/s00134-012-2745-3

APA

Huber, W., Mair, S., Götz, S. Q., Tschirdewahn, J., Siegel, J., Schmid, R. M., & Saugel, B. (2013). Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients. INTENS CARE MED, 39(1), 146-50. https://doi.org/10.1007/s00134-012-2745-3

Vancouver

Huber W, Mair S, Götz SQ, Tschirdewahn J, Siegel J, Schmid RM et al. Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients. INTENS CARE MED. 2013 Jan 1;39(1):146-50. https://doi.org/10.1007/s00134-012-2745-3

Bibtex

@article{b534190001f145c798dad09404117407,
title = "Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients",
abstract = "PURPOSE: With regard to large inter-individual variability of height, body weight (BW), and age, several hemodynamic parameters are adjusted for biometric data. This also applies to extravascular lung water (EVLW), which traditionally was indexed to actual BW (BW-act) resulting in EVLW-index (EVLWI; i.e., EVLWI-act). Since indexation to BW-act might inappropriately diminish EVLWI-act in obese patients, the indexation has been changed to predicted BW (BW-pred) resulting in EVLWI-pred. BW-pred is a weight estimation formula calculated from height and gender that has not been derived from population-based data. The aim of the study was to investigate the independent association of biometric data with EVLW.METHODS: We analyzed a hemodynamic monitoring database including 3,691 transpulmonary thermodilution-derived EVLW measurements (234 consecutive patients; intensive care unit of a university hospital). We performed univariate and multivariate analyses regarding the association of biometric data with the first EVLW measurement and the mean EVLW value of each patient.RESULTS: In univariate analysis, the first EVLW significantly correlated with height (r = 0.254; p < 0.001), but neither with age nor BW-act. Similar findings were made in the analysis of the patients' EVLW means of all measurements ({"}one point per patient{"}). In multivariate analysis (primary endpoint), including BW-act, height, age, and gender, only height was independently associated with EVLW, with each centimeter of height increasing the first measurement of EVLW by 6.882 mL (p < 0.001) and mean EVLW by 6.727 mL (p < 0.001).CONCLUSIONS: Height is the only biometric parameter independently associated with the first and mean EVLW. In adult patients, EVLW should be indexed to height.",
keywords = "Age Factors, Biometry, Body Height, Body Weight, Extravascular Lung Water, Female, Humans, Individuality, Intensive Care Units, Male, Middle Aged, Sex Factors, Thermodilution",
author = "Wolfgang Huber and Sebastian Mair and G{\"o}tz, {Simon Q} and Julia Tschirdewahn and Johanna Siegel and Schmid, {Roland M} and Bernd Saugel",
year = "2013",
month = jan,
day = "1",
doi = "10.1007/s00134-012-2745-3",
language = "English",
volume = "39",
pages = "146--50",
journal = "INTENS CARE MED",
issn = "0342-4642",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Extravascular lung water and its association with weight, height, age, and gender: a study in intensive care unit patients

AU - Huber, Wolfgang

AU - Mair, Sebastian

AU - Götz, Simon Q

AU - Tschirdewahn, Julia

AU - Siegel, Johanna

AU - Schmid, Roland M

AU - Saugel, Bernd

PY - 2013/1/1

Y1 - 2013/1/1

N2 - PURPOSE: With regard to large inter-individual variability of height, body weight (BW), and age, several hemodynamic parameters are adjusted for biometric data. This also applies to extravascular lung water (EVLW), which traditionally was indexed to actual BW (BW-act) resulting in EVLW-index (EVLWI; i.e., EVLWI-act). Since indexation to BW-act might inappropriately diminish EVLWI-act in obese patients, the indexation has been changed to predicted BW (BW-pred) resulting in EVLWI-pred. BW-pred is a weight estimation formula calculated from height and gender that has not been derived from population-based data. The aim of the study was to investigate the independent association of biometric data with EVLW.METHODS: We analyzed a hemodynamic monitoring database including 3,691 transpulmonary thermodilution-derived EVLW measurements (234 consecutive patients; intensive care unit of a university hospital). We performed univariate and multivariate analyses regarding the association of biometric data with the first EVLW measurement and the mean EVLW value of each patient.RESULTS: In univariate analysis, the first EVLW significantly correlated with height (r = 0.254; p < 0.001), but neither with age nor BW-act. Similar findings were made in the analysis of the patients' EVLW means of all measurements ("one point per patient"). In multivariate analysis (primary endpoint), including BW-act, height, age, and gender, only height was independently associated with EVLW, with each centimeter of height increasing the first measurement of EVLW by 6.882 mL (p < 0.001) and mean EVLW by 6.727 mL (p < 0.001).CONCLUSIONS: Height is the only biometric parameter independently associated with the first and mean EVLW. In adult patients, EVLW should be indexed to height.

AB - PURPOSE: With regard to large inter-individual variability of height, body weight (BW), and age, several hemodynamic parameters are adjusted for biometric data. This also applies to extravascular lung water (EVLW), which traditionally was indexed to actual BW (BW-act) resulting in EVLW-index (EVLWI; i.e., EVLWI-act). Since indexation to BW-act might inappropriately diminish EVLWI-act in obese patients, the indexation has been changed to predicted BW (BW-pred) resulting in EVLWI-pred. BW-pred is a weight estimation formula calculated from height and gender that has not been derived from population-based data. The aim of the study was to investigate the independent association of biometric data with EVLW.METHODS: We analyzed a hemodynamic monitoring database including 3,691 transpulmonary thermodilution-derived EVLW measurements (234 consecutive patients; intensive care unit of a university hospital). We performed univariate and multivariate analyses regarding the association of biometric data with the first EVLW measurement and the mean EVLW value of each patient.RESULTS: In univariate analysis, the first EVLW significantly correlated with height (r = 0.254; p < 0.001), but neither with age nor BW-act. Similar findings were made in the analysis of the patients' EVLW means of all measurements ("one point per patient"). In multivariate analysis (primary endpoint), including BW-act, height, age, and gender, only height was independently associated with EVLW, with each centimeter of height increasing the first measurement of EVLW by 6.882 mL (p < 0.001) and mean EVLW by 6.727 mL (p < 0.001).CONCLUSIONS: Height is the only biometric parameter independently associated with the first and mean EVLW. In adult patients, EVLW should be indexed to height.

KW - Age Factors

KW - Biometry

KW - Body Height

KW - Body Weight

KW - Extravascular Lung Water

KW - Female

KW - Humans

KW - Individuality

KW - Intensive Care Units

KW - Male

KW - Middle Aged

KW - Sex Factors

KW - Thermodilution

U2 - 10.1007/s00134-012-2745-3

DO - 10.1007/s00134-012-2745-3

M3 - SCORING: Journal article

C2 - 23160768

VL - 39

SP - 146

EP - 150

JO - INTENS CARE MED

JF - INTENS CARE MED

SN - 0342-4642

IS - 1

ER -