External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy.

Standard

External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy. / Zorn, Kevin C; Gallina, Andrea; Hutterer, Georg C; Walz, Jochen; Shalhav, Arieh L; Zagaja, Gregory P; Valiquette, Luc; Gofrit, Ofer N; Orvieto, Marcelo A; Taxy, Jerome B; Karakiewicz, Pierre I.

In: J ENDOUROL, Vol. 21, No. 11, 11, 2007, p. 1345-1351.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Zorn, KC, Gallina, A, Hutterer, GC, Walz, J, Shalhav, AL, Zagaja, GP, Valiquette, L, Gofrit, ON, Orvieto, MA, Taxy, JB & Karakiewicz, PI 2007, 'External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy.', J ENDOUROL, vol. 21, no. 11, 11, pp. 1345-1351. <http://www.ncbi.nlm.nih.gov/pubmed/18042028?dopt=Citation>

APA

Zorn, K. C., Gallina, A., Hutterer, G. C., Walz, J., Shalhav, A. L., Zagaja, G. P., Valiquette, L., Gofrit, O. N., Orvieto, M. A., Taxy, J. B., & Karakiewicz, P. I. (2007). External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy. J ENDOUROL, 21(11), 1345-1351. [11]. http://www.ncbi.nlm.nih.gov/pubmed/18042028?dopt=Citation

Vancouver

Zorn KC, Gallina A, Hutterer GC, Walz J, Shalhav AL, Zagaja GP et al. External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy. J ENDOUROL. 2007;21(11):1345-1351. 11.

Bibtex

@article{33a63d45bf5442779d08374027ce6a79,
title = "External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy.",
abstract = "BACKGROUND AND PURPOSE: Several staging tools have been developed for open radical prostatectomy (ORP) patients. However, the validity of these tools has never been formally tested in patients treated with robot-assisted laparoscopic radical prostatectomy (RALP). We tested the accuracy of an ORP-derived nomogram in predicting the rate of extracapsular extension (ECE) in a large RALP cohort. PATIENTS AND METHODS: Serum prostate specific antigen (PSA) and side-specific clinical stage and biopsy Gleason sum information were used in a previously validated nomogram predicting side-specific ECE. The nomogram-derived predictions were compared with the observed rate of ECE, and the accuracy of the predictions was quantified. Each prostate lobe was analyzed independently. As complete data were available for 576 patients, the analyses targeted 1152 prostate lobes. Median age and serum PSA concentration at radical prostatectomy were 60 years and 5.4 ng/mL, respectively. RESULTS: The majority of side-specific clinical stages were T(1c) (993; 86.2%). Most side-specific biopsy Gleason sums were 6 (572; 49.7%). The median side-specific percentages of positive cores and of cancer were, respectively, 20.0% and 5.0%. At final pathologic review, 107 patients (18.6%) had ECE, and side-specific ECE was present in 117 patients (20.3%). The nomogram was 89% accurate in the RALP cohort v 84% in the previously reported ORP validation. CONCLUSIONS: The ORP side-specific ECE nomogram is highly accurate in the RALP population, suggesting that predictive and possibly prognostic tools developed in ORP patients may be equally accurate in their RALP counterparts.",
author = "Zorn, {Kevin C} and Andrea Gallina and Hutterer, {Georg C} and Jochen Walz and Shalhav, {Arieh L} and Zagaja, {Gregory P} and Luc Valiquette and Gofrit, {Ofer N} and Orvieto, {Marcelo A} and Taxy, {Jerome B} and Karakiewicz, {Pierre I}",
year = "2007",
language = "Deutsch",
volume = "21",
pages = "1345--1351",
journal = "J ENDOUROL",
issn = "0892-7790",
publisher = "Mary Ann Liebert Inc.",
number = "11",

}

RIS

TY - JOUR

T1 - External validation of a nomogram for prediction of side-specific extracapsular extension at robotic radical prostatectomy.

AU - Zorn, Kevin C

AU - Gallina, Andrea

AU - Hutterer, Georg C

AU - Walz, Jochen

AU - Shalhav, Arieh L

AU - Zagaja, Gregory P

AU - Valiquette, Luc

AU - Gofrit, Ofer N

AU - Orvieto, Marcelo A

AU - Taxy, Jerome B

AU - Karakiewicz, Pierre I

PY - 2007

Y1 - 2007

N2 - BACKGROUND AND PURPOSE: Several staging tools have been developed for open radical prostatectomy (ORP) patients. However, the validity of these tools has never been formally tested in patients treated with robot-assisted laparoscopic radical prostatectomy (RALP). We tested the accuracy of an ORP-derived nomogram in predicting the rate of extracapsular extension (ECE) in a large RALP cohort. PATIENTS AND METHODS: Serum prostate specific antigen (PSA) and side-specific clinical stage and biopsy Gleason sum information were used in a previously validated nomogram predicting side-specific ECE. The nomogram-derived predictions were compared with the observed rate of ECE, and the accuracy of the predictions was quantified. Each prostate lobe was analyzed independently. As complete data were available for 576 patients, the analyses targeted 1152 prostate lobes. Median age and serum PSA concentration at radical prostatectomy were 60 years and 5.4 ng/mL, respectively. RESULTS: The majority of side-specific clinical stages were T(1c) (993; 86.2%). Most side-specific biopsy Gleason sums were 6 (572; 49.7%). The median side-specific percentages of positive cores and of cancer were, respectively, 20.0% and 5.0%. At final pathologic review, 107 patients (18.6%) had ECE, and side-specific ECE was present in 117 patients (20.3%). The nomogram was 89% accurate in the RALP cohort v 84% in the previously reported ORP validation. CONCLUSIONS: The ORP side-specific ECE nomogram is highly accurate in the RALP population, suggesting that predictive and possibly prognostic tools developed in ORP patients may be equally accurate in their RALP counterparts.

AB - BACKGROUND AND PURPOSE: Several staging tools have been developed for open radical prostatectomy (ORP) patients. However, the validity of these tools has never been formally tested in patients treated with robot-assisted laparoscopic radical prostatectomy (RALP). We tested the accuracy of an ORP-derived nomogram in predicting the rate of extracapsular extension (ECE) in a large RALP cohort. PATIENTS AND METHODS: Serum prostate specific antigen (PSA) and side-specific clinical stage and biopsy Gleason sum information were used in a previously validated nomogram predicting side-specific ECE. The nomogram-derived predictions were compared with the observed rate of ECE, and the accuracy of the predictions was quantified. Each prostate lobe was analyzed independently. As complete data were available for 576 patients, the analyses targeted 1152 prostate lobes. Median age and serum PSA concentration at radical prostatectomy were 60 years and 5.4 ng/mL, respectively. RESULTS: The majority of side-specific clinical stages were T(1c) (993; 86.2%). Most side-specific biopsy Gleason sums were 6 (572; 49.7%). The median side-specific percentages of positive cores and of cancer were, respectively, 20.0% and 5.0%. At final pathologic review, 107 patients (18.6%) had ECE, and side-specific ECE was present in 117 patients (20.3%). The nomogram was 89% accurate in the RALP cohort v 84% in the previously reported ORP validation. CONCLUSIONS: The ORP side-specific ECE nomogram is highly accurate in the RALP population, suggesting that predictive and possibly prognostic tools developed in ORP patients may be equally accurate in their RALP counterparts.

M3 - SCORING: Zeitschriftenaufsatz

VL - 21

SP - 1345

EP - 1351

JO - J ENDOUROL

JF - J ENDOUROL

SN - 0892-7790

IS - 11

M1 - 11

ER -