External quality assurance of circulating tumor cell enumeration using the CellSearch(®) system: a feasibility study.

  • Jaco Kraan
  • Stefan Sleijfer
  • Michiel H Strijbos
  • Michail Ignatiadis
  • Dieter Peeters
  • Jean-Yves Pierga
  • Francoise Farace
  • Sabine Riethdorf
  • Tanja Fehm
  • Laura Zorzino
  • Arjan G J Tibbe
  • Marisa Maestro
  • Rafael Gisbert-Criado
  • Graeme Denton
  • de Bono
  • S Johann
  • Caroline Dive
  • John A Foekens
  • Jan W Gratama

Related Research units

Abstract

Circulating tumor cells (CTCs) are cells that have detached from solid tumors and entered the blood. CTCs can be detected, among others, by semi-automated immunomagnetic enrichment and image cytometry using CellSearch® (Veridex, Raritan, NJ). We studied the feasibility of external quality assurance (EQA) of the entire CellSearch procedure from blood draw to interpretation of results in multiple laboratories.

Bibliographical data

Original languageEnglish
Article number2
ISSN1552-4949
Publication statusPublished - 2011
pubmed 21337491