Expression of SOX9 and SOX10 in central neuroepithelial tumor.
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Expression of SOX9 and SOX10 in central neuroepithelial tumor. / Kordes, Uwe; Hagel, C.
In: J NEURO-ONCOL, Vol. 80, No. 2, 2, 2006, p. 151-155.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Expression of SOX9 and SOX10 in central neuroepithelial tumor.
AU - Kordes, Uwe
AU - Hagel, C
PY - 2006
Y1 - 2006
N2 - The SOX group E transcription factors play an integral role in the specification and differentiation of astrocytes and oligodendrocytes. We have examined the pattern of expression for SOX9 and SOX10 in primary brain tumors by immunohistochemistry. Pediatric and adult high grade tumors display strong nuclear staining for both SOX9 and SOX10 (astrocytic, oligodendroglial and primitive neuroectodermal tumors). In comparison pediatric pilocytic astrocytoma express much less SOX9 and SOX10. Reactive astrogliosis is characterized by an increase of SOX9 only.
AB - The SOX group E transcription factors play an integral role in the specification and differentiation of astrocytes and oligodendrocytes. We have examined the pattern of expression for SOX9 and SOX10 in primary brain tumors by immunohistochemistry. Pediatric and adult high grade tumors display strong nuclear staining for both SOX9 and SOX10 (astrocytic, oligodendroglial and primitive neuroectodermal tumors). In comparison pediatric pilocytic astrocytoma express much less SOX9 and SOX10. Reactive astrogliosis is characterized by an increase of SOX9 only.
M3 - SCORING: Zeitschriftenaufsatz
VL - 80
SP - 151
EP - 155
JO - J NEURO-ONCOL
JF - J NEURO-ONCOL
SN - 0167-594X
IS - 2
M1 - 2
ER -