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Expression of kynurenine aminotransferases in the rat retina during development

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Expression of kynurenine aminotransferases in the rat retina during development. / Rejdak, Robert; Shenk, Yana; Schuettauf, Frank; Turski, Waldemar A; Okuno, Etsuo; Zagorski, Zbigniew; Zrenner, Eberhart; Kohler, Konrad.

In: VISION RES, Vol. 44, No. 1, 01.2004, p. 1-7.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Rejdak, R, Shenk, Y, Schuettauf, F, Turski, WA, Okuno, E, Zagorski, Z, Zrenner, E & Kohler, K 2004, 'Expression of kynurenine aminotransferases in the rat retina during development', VISION RES, vol. 44, no. 1, pp. 1-7. https://doi.org/10.1016/j.visres.2003.07.007

APA

Rejdak, R., Shenk, Y., Schuettauf, F., Turski, W. A., Okuno, E., Zagorski, Z., Zrenner, E., & Kohler, K. (2004). Expression of kynurenine aminotransferases in the rat retina during development. VISION RES, 44(1), 1-7. https://doi.org/10.1016/j.visres.2003.07.007

Vancouver

Rejdak R, Shenk Y, Schuettauf F, Turski WA, Okuno E, Zagorski Z et al. Expression of kynurenine aminotransferases in the rat retina during development. VISION RES. 2004 Jan;44(1):1-7. https://doi.org/10.1016/j.visres.2003.07.007

Bibtex

@article{0a1dfadcf8b642e5953d3cb136f84bf1,
title = "Expression of kynurenine aminotransferases in the rat retina during development",
abstract = "The study investigates the cellular expression of kynurenine aminotransferases (KAT I and II) in the rat retina during development. At P1 (the day of birth) and P7 (the 7th day after birth), KAT I expression was observed in the inner plexiform layer (IPL), the fiber layer (FL), and in vertically running processes in the ganglion cell layer (GCL) (but not in the cell bodies). At P14 (the 14th day after birth) a strong KAT I immunoreactivity was observed in M{\"u}ller cell endfeet. KAT II was expressed in the IPL, the FL, and in cells in the GCL at P1 and P7. From P14 on, KAT II expression in the IPL decreased. Double labeling revealed that KAT I was expressed in M{\"u}ller cell endfeet, whilst KAT II both on retinal ganglion cells (RGC) and M{\"u}ller cell endfeet. In conclusion, KAT I and II are present in the rat retina during development. The heterogeneity of the KAT developmental profiles possibly reflects a neuromodulatory role in the retinal differentiation.",
keywords = "Animals, Fluorescence, Immunohistochemistry, Rats, Retina/enzymology, Transaminases/metabolism",
author = "Robert Rejdak and Yana Shenk and Frank Schuettauf and Turski, {Waldemar A} and Etsuo Okuno and Zbigniew Zagorski and Eberhart Zrenner and Konrad Kohler",
year = "2004",
month = jan,
doi = "10.1016/j.visres.2003.07.007",
language = "English",
volume = "44",
pages = "1--7",
journal = "VISION RES",
issn = "0042-6989",
publisher = "Elsevier Limited",
number = "1",

}

RIS

TY - JOUR

T1 - Expression of kynurenine aminotransferases in the rat retina during development

AU - Rejdak, Robert

AU - Shenk, Yana

AU - Schuettauf, Frank

AU - Turski, Waldemar A

AU - Okuno, Etsuo

AU - Zagorski, Zbigniew

AU - Zrenner, Eberhart

AU - Kohler, Konrad

PY - 2004/1

Y1 - 2004/1

N2 - The study investigates the cellular expression of kynurenine aminotransferases (KAT I and II) in the rat retina during development. At P1 (the day of birth) and P7 (the 7th day after birth), KAT I expression was observed in the inner plexiform layer (IPL), the fiber layer (FL), and in vertically running processes in the ganglion cell layer (GCL) (but not in the cell bodies). At P14 (the 14th day after birth) a strong KAT I immunoreactivity was observed in Müller cell endfeet. KAT II was expressed in the IPL, the FL, and in cells in the GCL at P1 and P7. From P14 on, KAT II expression in the IPL decreased. Double labeling revealed that KAT I was expressed in Müller cell endfeet, whilst KAT II both on retinal ganglion cells (RGC) and Müller cell endfeet. In conclusion, KAT I and II are present in the rat retina during development. The heterogeneity of the KAT developmental profiles possibly reflects a neuromodulatory role in the retinal differentiation.

AB - The study investigates the cellular expression of kynurenine aminotransferases (KAT I and II) in the rat retina during development. At P1 (the day of birth) and P7 (the 7th day after birth), KAT I expression was observed in the inner plexiform layer (IPL), the fiber layer (FL), and in vertically running processes in the ganglion cell layer (GCL) (but not in the cell bodies). At P14 (the 14th day after birth) a strong KAT I immunoreactivity was observed in Müller cell endfeet. KAT II was expressed in the IPL, the FL, and in cells in the GCL at P1 and P7. From P14 on, KAT II expression in the IPL decreased. Double labeling revealed that KAT I was expressed in Müller cell endfeet, whilst KAT II both on retinal ganglion cells (RGC) and Müller cell endfeet. In conclusion, KAT I and II are present in the rat retina during development. The heterogeneity of the KAT developmental profiles possibly reflects a neuromodulatory role in the retinal differentiation.

KW - Animals

KW - Fluorescence

KW - Immunohistochemistry

KW - Rats

KW - Retina/enzymology

KW - Transaminases/metabolism

U2 - 10.1016/j.visres.2003.07.007

DO - 10.1016/j.visres.2003.07.007

M3 - SCORING: Journal article

C2 - 14599566

VL - 44

SP - 1

EP - 7

JO - VISION RES

JF - VISION RES

SN - 0042-6989

IS - 1

ER -