Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia.

  • Tim Luetkens
  • Philippe Schafhausen
  • Frederike Uhlich
  • Tim Stasche
  • Ruken Özge Akbulak
  • Britta M Bartels
  • York Hildebrandt
  • Artur Gontarewicz
  • Sebastian Kobold
  • Sabrina Meyer
  • Maja Gordic
  • Katrin Bartels
  • Nesrine Lajmi
  • Yanran Cao
  • Nicolaus Kröger
  • Carsten Bokemeyer
  • Tim Brümmendorf
  • Djordje Atanackovic

Abstract

Cancer-testis (CT) antigens represent attractive targets for tumor immunotherapy based on their tumor-restricted expression and immunogenicity. However, a broad picture of the expression of CT antigens and associated humoral immune responses in chronic myeloid leukemia (CML) is still missing.

Bibliographical data

Original languageGerman
Article number12
ISSN0145-2126
Publication statusPublished - 2010
pubmed 20409582