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Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region

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Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region. / Fu, Zuyi; Liao, Zili; Zhang, Jinlin; Zhan, Xianzhang; Lin, Weidong; Liu, Fang Zhou; Su, Xi; Deng, Hai; Fang, Xianhong; Liao, Hongtao; Wang, Hongyue; Wu, Shulin; Xue, Yumei; Ouyang, Feifan.

In: FRONT CARDIOVASC MED, Vol. 8, 793903, 2021.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Fu, Z, Liao, Z, Zhang, J, Zhan, X, Lin, W, Liu, FZ, Su, X, Deng, H, Fang, X, Liao, H, Wang, H, Wu, S, Xue, Y & Ouyang, F 2021, 'Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region', FRONT CARDIOVASC MED, vol. 8, 793903. https://doi.org/10.3389/fcvm.2021.793903

APA

Fu, Z., Liao, Z., Zhang, J., Zhan, X., Lin, W., Liu, F. Z., Su, X., Deng, H., Fang, X., Liao, H., Wang, H., Wu, S., Xue, Y., & Ouyang, F. (2021). Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region. FRONT CARDIOVASC MED, 8, [793903]. https://doi.org/10.3389/fcvm.2021.793903

Vancouver

Fu Z, Liao Z, Zhang J, Zhan X, Lin W, Liu FZ et al. Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region. FRONT CARDIOVASC MED. 2021;8. 793903. https://doi.org/10.3389/fcvm.2021.793903

Bibtex

@article{0bbd09a7116d47bfb272723359c9f622,
title = "Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region",
abstract = "Background: Catheter ablation target at the site with large His activation in the left ventricle poses a high risk of atrioventricular (AV) block. We aimed to identify far-field (FF) and near-field (NF) His activation at left upper septum (LUS).Methods: Three-D mapping of the aortic root and left ventricle was performed in 12 dogs. Two sites located at either the base or apex of the triangle interposed between the hinges of the the noncornary coronary cusp (NCC) - right coronary cusp (RCC) were chosen for a single radiofrequency (RF) application. Bipolar and unipolar pacing with different outputs at both sites was attempted to discern NF and FF His activation.Results: The sites chosen for NF and FF ablation were located at the base and apex of the triangle, which were 8.03 ± 1.18 mm (group 1) and 3.42 ± 0.61 mm (group 2) away from the RCC-NCC junction. Lower A/V ratios were found in group 1. Pacing could not differentiate NF from FF His activation. In group 1, ablation resulted in III degree AV block in all 6 dogs, whereas neither PR prolongation nor AV block occurred in group 2. Pathologic examination of group 1 showed complete/partial necrosis of the His bundle (HB) and left bundle branch in all 6 dogs. In group 2, no necrosis of the HB was seen in the 6/6 dogs.Conclusion: Anatomical localization in the triangle of RCC-NCC junction can help differentiate NF from FF His activation.",
author = "Zuyi Fu and Zili Liao and Jinlin Zhang and Xianzhang Zhan and Weidong Lin and Liu, {Fang Zhou} and Xi Su and Hai Deng and Xianhong Fang and Hongtao Liao and Hongyue Wang and Shulin Wu and Yumei Xue and Feifan Ouyang",
note = "Copyright {\textcopyright} 2022 Fu, Liao, Zhang, Zhan, Lin, Liu, Su, Deng, Fang, Liao, Wang, Wu, Xue and Ouyang.",
year = "2021",
doi = "10.3389/fcvm.2021.793903",
language = "English",
volume = "8",
journal = "FRONT CARDIOVASC MED",
issn = "2297-055X",
publisher = "Frontiers Media S. A.",

}

RIS

TY - JOUR

T1 - Experimental Findings and Clinical-Pathologic Correlation of Radiofrequency Catheter Ablation at the Left Ventricle Para-Hisian Region

AU - Fu, Zuyi

AU - Liao, Zili

AU - Zhang, Jinlin

AU - Zhan, Xianzhang

AU - Lin, Weidong

AU - Liu, Fang Zhou

AU - Su, Xi

AU - Deng, Hai

AU - Fang, Xianhong

AU - Liao, Hongtao

AU - Wang, Hongyue

AU - Wu, Shulin

AU - Xue, Yumei

AU - Ouyang, Feifan

N1 - Copyright © 2022 Fu, Liao, Zhang, Zhan, Lin, Liu, Su, Deng, Fang, Liao, Wang, Wu, Xue and Ouyang.

PY - 2021

Y1 - 2021

N2 - Background: Catheter ablation target at the site with large His activation in the left ventricle poses a high risk of atrioventricular (AV) block. We aimed to identify far-field (FF) and near-field (NF) His activation at left upper septum (LUS).Methods: Three-D mapping of the aortic root and left ventricle was performed in 12 dogs. Two sites located at either the base or apex of the triangle interposed between the hinges of the the noncornary coronary cusp (NCC) - right coronary cusp (RCC) were chosen for a single radiofrequency (RF) application. Bipolar and unipolar pacing with different outputs at both sites was attempted to discern NF and FF His activation.Results: The sites chosen for NF and FF ablation were located at the base and apex of the triangle, which were 8.03 ± 1.18 mm (group 1) and 3.42 ± 0.61 mm (group 2) away from the RCC-NCC junction. Lower A/V ratios were found in group 1. Pacing could not differentiate NF from FF His activation. In group 1, ablation resulted in III degree AV block in all 6 dogs, whereas neither PR prolongation nor AV block occurred in group 2. Pathologic examination of group 1 showed complete/partial necrosis of the His bundle (HB) and left bundle branch in all 6 dogs. In group 2, no necrosis of the HB was seen in the 6/6 dogs.Conclusion: Anatomical localization in the triangle of RCC-NCC junction can help differentiate NF from FF His activation.

AB - Background: Catheter ablation target at the site with large His activation in the left ventricle poses a high risk of atrioventricular (AV) block. We aimed to identify far-field (FF) and near-field (NF) His activation at left upper septum (LUS).Methods: Three-D mapping of the aortic root and left ventricle was performed in 12 dogs. Two sites located at either the base or apex of the triangle interposed between the hinges of the the noncornary coronary cusp (NCC) - right coronary cusp (RCC) were chosen for a single radiofrequency (RF) application. Bipolar and unipolar pacing with different outputs at both sites was attempted to discern NF and FF His activation.Results: The sites chosen for NF and FF ablation were located at the base and apex of the triangle, which were 8.03 ± 1.18 mm (group 1) and 3.42 ± 0.61 mm (group 2) away from the RCC-NCC junction. Lower A/V ratios were found in group 1. Pacing could not differentiate NF from FF His activation. In group 1, ablation resulted in III degree AV block in all 6 dogs, whereas neither PR prolongation nor AV block occurred in group 2. Pathologic examination of group 1 showed complete/partial necrosis of the His bundle (HB) and left bundle branch in all 6 dogs. In group 2, no necrosis of the HB was seen in the 6/6 dogs.Conclusion: Anatomical localization in the triangle of RCC-NCC junction can help differentiate NF from FF His activation.

U2 - 10.3389/fcvm.2021.793903

DO - 10.3389/fcvm.2021.793903

M3 - SCORING: Journal article

C2 - 35155606

VL - 8

JO - FRONT CARDIOVASC MED

JF - FRONT CARDIOVASC MED

SN - 2297-055X

M1 - 793903

ER -