Executive summary. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK
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Executive summary. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK. / Hansmann, Georg; Apitz, Christian; Abdul-Khaliq, Hashim; Alastalo, Tero-Pekka; Beerbaum, Phillip; Bonnet, Damien; Dubowy, Karl-Otto; Gorenflo, Matthias; Hager, Alfred; Hilgendorff, Anne; Kaestner, Michael; Koestenberger, Martin; Koskenvuo, Juha W; Kozlik-Feldmann, Rainer; Kuehne, Titus; Lammers, Astrid E; Latus, Heiner; Michel-Behnke, Ina; Miera, Oliver; Moledina, Shahin; Muthurangu, Vivek; Pattathu, Joseph; Schranz, Dietmar; Warnecke, Gregor; Zartner, Peter.
In: HEART, Vol. 102 , No. Suppl 2, 05.2016, p. ii86-100.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
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T1 - Executive summary. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK
AU - Hansmann, Georg
AU - Apitz, Christian
AU - Abdul-Khaliq, Hashim
AU - Alastalo, Tero-Pekka
AU - Beerbaum, Phillip
AU - Bonnet, Damien
AU - Dubowy, Karl-Otto
AU - Gorenflo, Matthias
AU - Hager, Alfred
AU - Hilgendorff, Anne
AU - Kaestner, Michael
AU - Koestenberger, Martin
AU - Koskenvuo, Juha W
AU - Kozlik-Feldmann, Rainer
AU - Kuehne, Titus
AU - Lammers, Astrid E
AU - Latus, Heiner
AU - Michel-Behnke, Ina
AU - Miera, Oliver
AU - Moledina, Shahin
AU - Muthurangu, Vivek
AU - Pattathu, Joseph
AU - Schranz, Dietmar
AU - Warnecke, Gregor
AU - Zartner, Peter
N1 - Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
PY - 2016/5
Y1 - 2016/5
N2 - UNLABELLED: : The European Paediatric Pulmonary Vascular Disease (PVD) Network is a registered, non-profit organisation that strives to define and develop effective, innovative diagnostic methods and treatment options in all forms of paediatric pulmonary hypertensive vascular disease, including specific forms such as pulmonary arterial hypertension (PAH)-congenital heart disease, pulmonary hypertension (PH) associated with bronchopulmonary dysplasia, persistent PH of the newborn, and related cardiac dysfunction.METHODS: The writing group members conducted searches of the PubMed/MEDLINE bibliographic database (1990-2015) and held five face-to-face meetings with votings. Clinical trials, guidelines, and reviews limited to paediatric data were searched using the terms 'pulmonary hypertensioń' and 5-10 other keywords, as outlined in the other nine articles of this special issue. Class of recommendation (COR) and level of evidence (LOE) were assigned based on European Society of Cardiology/American Heart Association definitions and on paediatric data only, or on adult studies that included >10% children.RESULTS: A total of 9 original consensus articles with graded recommendations (COR/LOE) were developed, and are summarised here. The topics included diagnosis/monitoring, genetics/biomarker, cardiac catheterisation, echocardiography, cardiac magnetic resonance/chest CT, associated forms of PH, intensive care unit/ventricular assist device/lung transplantation, and treatment of paediatric PAH.CONCLUSIONS: The multipaper expert consensus statement of the European Paediatric PVD Network provides a specific, comprehensive, detailed but practical framework for the optimal clinical care of children with PH.
AB - UNLABELLED: : The European Paediatric Pulmonary Vascular Disease (PVD) Network is a registered, non-profit organisation that strives to define and develop effective, innovative diagnostic methods and treatment options in all forms of paediatric pulmonary hypertensive vascular disease, including specific forms such as pulmonary arterial hypertension (PAH)-congenital heart disease, pulmonary hypertension (PH) associated with bronchopulmonary dysplasia, persistent PH of the newborn, and related cardiac dysfunction.METHODS: The writing group members conducted searches of the PubMed/MEDLINE bibliographic database (1990-2015) and held five face-to-face meetings with votings. Clinical trials, guidelines, and reviews limited to paediatric data were searched using the terms 'pulmonary hypertensioń' and 5-10 other keywords, as outlined in the other nine articles of this special issue. Class of recommendation (COR) and level of evidence (LOE) were assigned based on European Society of Cardiology/American Heart Association definitions and on paediatric data only, or on adult studies that included >10% children.RESULTS: A total of 9 original consensus articles with graded recommendations (COR/LOE) were developed, and are summarised here. The topics included diagnosis/monitoring, genetics/biomarker, cardiac catheterisation, echocardiography, cardiac magnetic resonance/chest CT, associated forms of PH, intensive care unit/ventricular assist device/lung transplantation, and treatment of paediatric PAH.CONCLUSIONS: The multipaper expert consensus statement of the European Paediatric PVD Network provides a specific, comprehensive, detailed but practical framework for the optimal clinical care of children with PH.
KW - Adolescent
KW - Child
KW - Child, Preschool
KW - Europe
KW - Humans
KW - Hypertension, Pulmonary/diagnosis
KW - Infant
KW - Infant, Newborn
KW - Societies, Medical
U2 - 10.1136/heartjnl-2015-309132
DO - 10.1136/heartjnl-2015-309132
M3 - Other (editorial matter etc.)
C2 - 27053701
VL - 102
SP - ii86-100
JO - HEART
JF - HEART
SN - 1355-6037
IS - Suppl 2
ER -