Examination of the Contributions of Maternal/Placental-Derived Galectin-1 to Pregnancy Outcome
Related Research units
Abstract
Galectin-1 (gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, is differentially expressed at the feto-maternal interface and appears to be functionally polyvalent, with a wide range of biological activities. However, the contributions of maternal and/or feto-placental gal-1 to the signaling networks promoting a healthy pregnancy are still being elucidated. This chapter discusses the methods commonly employed to study the maternal or feto-placental contribution of gal-1 during pregnancy in mice. The methods described here can be used to decipher the specific role of each source, e.g., maternal and/or feto-placental derived gal-1 in the orchestration of pregnancy-associated processes.
Bibliographical data
Original language | English |
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Title of host publication | Galectins : Methods and Protocols |
Editors | Sean R. Stowell, Connie M. Arthur, Richard D. Cummings |
REQUIRED books only: Number of pages | 17 |
Place of Publication | New York, NY |
Publisher | Humana Press |
Publication date | 2022 |
Edition | 1 |
Pages | 603-619 |
ISBN (Print) | 978-1-0716-2054-0 |
ISBN (Electronic) | 978-1-0716-2055-7 |
DOIs | |
Publication status | Published - 2022 |
Comment Deanary
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.
PubMed | 35320548 |
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