Evaluation of seven X-chromosomal short tandem repeat loci located within the Xq26 region.

  • Heike Rodig
  • Frank Kloep
  • Lydia Weissbach
  • Christa Augustin
  • Jeannett Edelmann
  • Sandra Hering
  • Reinhard Szibor
  • Frank Götz
  • Werner Brabetz

Related Research units

Abstract

In this study a set of 29 X-chromosomal short tandem repeats (STRs) located within the Xq26 region was evaluated. These STRs were found within the 133.14-133.45Mb region around the HPRTB locus. Evaluation of the microsatellites was performed with regard to polymorphism, reliable amplification, and low stutter artefacts. DXS10101, DXS10102, and DXS10103 were identified as those X-STRs with highest diversity; i.e. PIC values of 0.7174-0.8933. The locus DXS10101 was the optimal candidate for the integration in the commercial available test system Mentype Argus X-8 PCR amplification kit.

Bibliographical data

Original languageGerman
Article number3
ISSN1878-0326
Publication statusPublished - 2010
pubmed 20215031