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Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate

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Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate. / Tolle, Julia; Knipper, Sophie; Pose, Randi; Tennstedt, Pierre; Tilki, Derya; Graefen, Markus; Isbarn, Hendrik.

In: UROL INT, Vol. 105, No. 5-6, 2021, p. 408-413.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Tolle, J, Knipper, S, Pose, R, Tennstedt, P, Tilki, D, Graefen, M & Isbarn, H 2021, 'Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate', UROL INT, vol. 105, no. 5-6, pp. 408-413. https://doi.org/10.1159/000513657

APA

Tolle, J., Knipper, S., Pose, R., Tennstedt, P., Tilki, D., Graefen, M., & Isbarn, H. (2021). Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate. UROL INT, 105(5-6), 408-413. https://doi.org/10.1159/000513657

Vancouver

Tolle J, Knipper S, Pose R, Tennstedt P, Tilki D, Graefen M et al. Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate. UROL INT. 2021;105(5-6):408-413. https://doi.org/10.1159/000513657

Bibtex

@article{f422966eda3841318f72b9cbe73a60a0,
title = "Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate",
abstract = "INTRODUCTION: A history of transurethral surgery of the prostate is generally considered as a risk factor of adverse functional outcomes after radical prostatectomy (RP). We tested whether the risk of postoperative urinary incontinence (UIC) and erectile dysfunction (ED) after RP could be further substantiated in such patients.MATERIALS AND METHODS: We tested the effect of the following variables on UIC and ED rates 1 year after RP: residual prostate volume after transurethral desobstruction, the time from transurethral desobstruction to RP, the type of transurethral desobstruction (TURP vs. laser enucleation), age, and nerve-sparing surgery (yes vs. no). UIC was defined as usage of any pad except a safety pad. ED was defined as no sexual intercourse possible.RESULTS: Overall, 216 patients treated with RP between 2010 and 2019 in a tertiary care center were evaluated. All patients had previously undergone transurethral desobstruction. Regarding UIC analyses, only time from transurethral desobstruction to RP significantly influenced UIC rates (p = 0.003). Regarding ED rates, none of the tested variables reached statistical significance.CONCLUSION: The risk of UIC and ED after RP is substantial in men who had previously undergone transurethral desobstruction. The time from transurethral desobstruction to RP significantly impacts on the postoperative UIC rates. This observation should be further explored in future studies.",
keywords = "Aged, Erectile Dysfunction/epidemiology, Humans, Male, Middle Aged, Postoperative Complications/epidemiology, Prostatectomy/adverse effects, Reoperation, Retrospective Studies, Risk Assessment, Risk Factors, Transurethral Resection of Prostate, Urinary Incontinence/epidemiology",
author = "Julia Tolle and Sophie Knipper and Randi Pose and Pierre Tennstedt and Derya Tilki and Markus Graefen and Hendrik Isbarn",
note = "{\textcopyright} 2021 S. Karger AG, Basel.",
year = "2021",
doi = "10.1159/000513657",
language = "English",
volume = "105",
pages = "408--413",
journal = "UROL INT",
issn = "0042-1138",
publisher = "S. Karger AG",
number = "5-6",

}

RIS

TY - JOUR

T1 - Evaluation of Risk Factors for Adverse Functional Outcomes after Radical Prostatectomy in Patients with Previous Transurethral Surgery of the Prostate

AU - Tolle, Julia

AU - Knipper, Sophie

AU - Pose, Randi

AU - Tennstedt, Pierre

AU - Tilki, Derya

AU - Graefen, Markus

AU - Isbarn, Hendrik

N1 - © 2021 S. Karger AG, Basel.

PY - 2021

Y1 - 2021

N2 - INTRODUCTION: A history of transurethral surgery of the prostate is generally considered as a risk factor of adverse functional outcomes after radical prostatectomy (RP). We tested whether the risk of postoperative urinary incontinence (UIC) and erectile dysfunction (ED) after RP could be further substantiated in such patients.MATERIALS AND METHODS: We tested the effect of the following variables on UIC and ED rates 1 year after RP: residual prostate volume after transurethral desobstruction, the time from transurethral desobstruction to RP, the type of transurethral desobstruction (TURP vs. laser enucleation), age, and nerve-sparing surgery (yes vs. no). UIC was defined as usage of any pad except a safety pad. ED was defined as no sexual intercourse possible.RESULTS: Overall, 216 patients treated with RP between 2010 and 2019 in a tertiary care center were evaluated. All patients had previously undergone transurethral desobstruction. Regarding UIC analyses, only time from transurethral desobstruction to RP significantly influenced UIC rates (p = 0.003). Regarding ED rates, none of the tested variables reached statistical significance.CONCLUSION: The risk of UIC and ED after RP is substantial in men who had previously undergone transurethral desobstruction. The time from transurethral desobstruction to RP significantly impacts on the postoperative UIC rates. This observation should be further explored in future studies.

AB - INTRODUCTION: A history of transurethral surgery of the prostate is generally considered as a risk factor of adverse functional outcomes after radical prostatectomy (RP). We tested whether the risk of postoperative urinary incontinence (UIC) and erectile dysfunction (ED) after RP could be further substantiated in such patients.MATERIALS AND METHODS: We tested the effect of the following variables on UIC and ED rates 1 year after RP: residual prostate volume after transurethral desobstruction, the time from transurethral desobstruction to RP, the type of transurethral desobstruction (TURP vs. laser enucleation), age, and nerve-sparing surgery (yes vs. no). UIC was defined as usage of any pad except a safety pad. ED was defined as no sexual intercourse possible.RESULTS: Overall, 216 patients treated with RP between 2010 and 2019 in a tertiary care center were evaluated. All patients had previously undergone transurethral desobstruction. Regarding UIC analyses, only time from transurethral desobstruction to RP significantly influenced UIC rates (p = 0.003). Regarding ED rates, none of the tested variables reached statistical significance.CONCLUSION: The risk of UIC and ED after RP is substantial in men who had previously undergone transurethral desobstruction. The time from transurethral desobstruction to RP significantly impacts on the postoperative UIC rates. This observation should be further explored in future studies.

KW - Aged

KW - Erectile Dysfunction/epidemiology

KW - Humans

KW - Male

KW - Middle Aged

KW - Postoperative Complications/epidemiology

KW - Prostatectomy/adverse effects

KW - Reoperation

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Transurethral Resection of Prostate

KW - Urinary Incontinence/epidemiology

U2 - 10.1159/000513657

DO - 10.1159/000513657

M3 - SCORING: Journal article

C2 - 33789314

VL - 105

SP - 408

EP - 413

JO - UROL INT

JF - UROL INT

SN - 0042-1138

IS - 5-6

ER -