Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system

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Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system. / Pfefferle, Susanne; Reucher, Svenja; Nörz, Dominik Sebastian; Lütgehetmann, Marc.

In: EUROSURVEILLANCE, Vol. 25, No. 9, 04.03.2020.

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@article{b6926c9d89be463cb701c3e97b31a163,
title = "Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system",
abstract = "Facing the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), high-volume respiratory testing is demanded in laboratories worldwide. We evaluated the performance of a molecular assay for the detection of SARS-CoV-2 on a high-throughput platform, the cobas 6800, using the 'open channel' for integration of a laboratory-developed assay. We observed good analytical performance in clinical specimens. The fully automated workflow enables high-throughput testing with minimal hands-on time, while offering fast and reliable results.",
author = "Susanne Pfefferle and Svenja Reucher and N{\"o}rz, {Dominik Sebastian} and Marc L{\"u}tgehetmann",
year = "2020",
month = mar,
day = "4",
doi = "10.2807/1560-7917.ES.2020.25.9.2000152",
language = "English",
volume = "25",
journal = "EUROSURVEILLANCE",
issn = "1025-496X",
publisher = "Centre Europeen pour la Surveillance Epidemiologique du SIDA",
number = "9",

}

RIS

TY - JOUR

T1 - Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system

AU - Pfefferle, Susanne

AU - Reucher, Svenja

AU - Nörz, Dominik Sebastian

AU - Lütgehetmann, Marc

PY - 2020/3/4

Y1 - 2020/3/4

N2 - Facing the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), high-volume respiratory testing is demanded in laboratories worldwide. We evaluated the performance of a molecular assay for the detection of SARS-CoV-2 on a high-throughput platform, the cobas 6800, using the 'open channel' for integration of a laboratory-developed assay. We observed good analytical performance in clinical specimens. The fully automated workflow enables high-throughput testing with minimal hands-on time, while offering fast and reliable results.

AB - Facing the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), high-volume respiratory testing is demanded in laboratories worldwide. We evaluated the performance of a molecular assay for the detection of SARS-CoV-2 on a high-throughput platform, the cobas 6800, using the 'open channel' for integration of a laboratory-developed assay. We observed good analytical performance in clinical specimens. The fully automated workflow enables high-throughput testing with minimal hands-on time, while offering fast and reliable results.

U2 - 10.2807/1560-7917.ES.2020.25.9.2000152

DO - 10.2807/1560-7917.ES.2020.25.9.2000152

M3 - SCORING: Journal article

VL - 25

JO - EUROSURVEILLANCE

JF - EUROSURVEILLANCE

SN - 1025-496X

IS - 9

ER -