Escitalopram for the prevention of peginterferon-α2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial.

  • Martin Schaefer
  • Rahul Sarkar
  • Viola Knop
  • Susanne Effenberger
  • Astrid Friebe
  • Loni Heinze
  • Ulrich Spengler
  • Thomas Schlaepfer
  • Jens Reimer
  • Peter Buggisch
  • Johann Ockenga
  • Ralph Link
  • Michael Rentrop
  • Hans Weidenbach
  • Gwendolyn Fromm
  • Klaus Lieb
  • Thomas F Baumert
  • Andreas Heinz
  • Thomas Discher
  • Konrad Neumann
  • Stefan Zeuzem
  • Thomas Berg

Abstract

Depression is a major complication during treatment of chronic hepatitis C virus (HCV) infection with interferon-? (IFN-?). It is unclear whether antidepressants can prevent IFN-induced depression in patients without psychiatric risk factors.

Bibliographical data

Original languageEnglish
Article number2
ISSN0003-4819
Publication statusPublished - 2012
pubmed 22801672