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Epigenetics of kidney disease

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Epigenetics of kidney disease. / Wanner, Nicola; Bechtel-Walz, Wibke.

In: CELL TISSUE RES, Vol. 369, No. 1, 07.2017, p. 75-92.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Wanner, N & Bechtel-Walz, W 2017, 'Epigenetics of kidney disease', CELL TISSUE RES, vol. 369, no. 1, pp. 75-92. https://doi.org/10.1007/s00441-017-2588-x

APA

Wanner, N., & Bechtel-Walz, W. (2017). Epigenetics of kidney disease. CELL TISSUE RES, 369(1), 75-92. https://doi.org/10.1007/s00441-017-2588-x

Vancouver

Wanner N, Bechtel-Walz W. Epigenetics of kidney disease. CELL TISSUE RES. 2017 Jul;369(1):75-92. https://doi.org/10.1007/s00441-017-2588-x

Bibtex

@article{1c37dc02b7d64368b5f387b512b69ab7,
title = "Epigenetics of kidney disease",
abstract = "DNA methylation and histone modifications determine renal programming and the development and progression of renal disease. The identification of the way in which the renal cell epigenome is altered by environmental modifiers driving the onset and progression of renal diseases has extended our understanding of the pathophysiology of kidney disease progression. In this review, we focus on current knowledge concerning the implications of epigenetic modifications during renal disease from early development to chronic kidney disease progression including renal fibrosis, diabetic nephropathy and the translational potential of identifying new biomarkers and treatments for the prevention and therapy of chronic kidney disease and end-stage kidney disease.",
keywords = "Journal Article, Review",
author = "Nicola Wanner and Wibke Bechtel-Walz",
year = "2017",
month = jul,
doi = "10.1007/s00441-017-2588-x",
language = "English",
volume = "369",
pages = "75--92",
journal = "CELL TISSUE RES",
issn = "0302-766X",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Epigenetics of kidney disease

AU - Wanner, Nicola

AU - Bechtel-Walz, Wibke

PY - 2017/7

Y1 - 2017/7

N2 - DNA methylation and histone modifications determine renal programming and the development and progression of renal disease. The identification of the way in which the renal cell epigenome is altered by environmental modifiers driving the onset and progression of renal diseases has extended our understanding of the pathophysiology of kidney disease progression. In this review, we focus on current knowledge concerning the implications of epigenetic modifications during renal disease from early development to chronic kidney disease progression including renal fibrosis, diabetic nephropathy and the translational potential of identifying new biomarkers and treatments for the prevention and therapy of chronic kidney disease and end-stage kidney disease.

AB - DNA methylation and histone modifications determine renal programming and the development and progression of renal disease. The identification of the way in which the renal cell epigenome is altered by environmental modifiers driving the onset and progression of renal diseases has extended our understanding of the pathophysiology of kidney disease progression. In this review, we focus on current knowledge concerning the implications of epigenetic modifications during renal disease from early development to chronic kidney disease progression including renal fibrosis, diabetic nephropathy and the translational potential of identifying new biomarkers and treatments for the prevention and therapy of chronic kidney disease and end-stage kidney disease.

KW - Journal Article

KW - Review

U2 - 10.1007/s00441-017-2588-x

DO - 10.1007/s00441-017-2588-x

M3 - SCORING: Review article

C2 - 28286899

VL - 369

SP - 75

EP - 92

JO - CELL TISSUE RES

JF - CELL TISSUE RES

SN - 0302-766X

IS - 1

ER -