Epidemiology of rosacea in a population-based study of 161,269 German employees

TY - JOUR

T1 - Epidemiology of rosacea in a population-based study of 161,269 German employees

AU - Hilbring, Caroline

AU - Augustin, Matthias

AU - Kirsten, Natalia

AU - Mohr, Nicole

N1 - © 2021 The Authors. International Journal of Dermatology published by Wiley Periodicals LLC on behalf of the International Society of Dermatology.

PY - 2022/5

Y1 - 2022/5

N2 - BACKGROUND: Rosacea is a common chronic skin condition, but data on its epidemiology and related comorbidities are scarce.OBJECTIVES: To analyze the prevalence and associated cutaneous comorbidities of rosacea in Germany.METHODS: Voluntary dermatological full-body examinations were conducted between 2001 and 2016 in more than 500 German companies by experienced dermatologists and documented electronically. Point-prevalence rates were calculated, and associations were tested with chi-squared tests and logistic regression analysis.RESULTS: A total of 161,269 participants (mean age was 43.2 ± 10.9 years; 55.5% male) were included; 2.1% had rosacea (men: 2.1%, women 2.1%, mean age 50.7 ± 9.3 years). The prevalence of rosacea increased significantly with age (16-29 years: 0.3%; 30-39 years: 0.9%; 40-49 years: 2.0%; 50-59 years: 3.5%; 60-70 years: 5.7%). Furthermore, there was a significant decreasing prevalence from skin type I toward type IV (skin type I: 3.2%; II: 2.2%; III: 1.5%; IV: 0.4%). The most frequent dermatological comorbidities were: telangiectasia (OR = 2.5), folliculitis (OR = 1.8), seborrheic dermatitis (OR = 1.6), acne (OR = 1.6), tinea pedis (OR = 1.4), psoriasis (OR = 1.4), spider veins (OR = 1.1), and hemangioma (OR = 1.1).CONCLUSIONS: Rosacea is a common skin condition that is most prevalent above the age of 65 years. Rosacea patients have an increased risk for associated comorbidities. Therefore, the diagnostic and therapeutic process for rosacea patients must ensure an integrated, complete dermatological approach in terms of medical care.

AB - BACKGROUND: Rosacea is a common chronic skin condition, but data on its epidemiology and related comorbidities are scarce.OBJECTIVES: To analyze the prevalence and associated cutaneous comorbidities of rosacea in Germany.METHODS: Voluntary dermatological full-body examinations were conducted between 2001 and 2016 in more than 500 German companies by experienced dermatologists and documented electronically. Point-prevalence rates were calculated, and associations were tested with chi-squared tests and logistic regression analysis.RESULTS: A total of 161,269 participants (mean age was 43.2 ± 10.9 years; 55.5% male) were included; 2.1% had rosacea (men: 2.1%, women 2.1%, mean age 50.7 ± 9.3 years). The prevalence of rosacea increased significantly with age (16-29 years: 0.3%; 30-39 years: 0.9%; 40-49 years: 2.0%; 50-59 years: 3.5%; 60-70 years: 5.7%). Furthermore, there was a significant decreasing prevalence from skin type I toward type IV (skin type I: 3.2%; II: 2.2%; III: 1.5%; IV: 0.4%). The most frequent dermatological comorbidities were: telangiectasia (OR = 2.5), folliculitis (OR = 1.8), seborrheic dermatitis (OR = 1.6), acne (OR = 1.6), tinea pedis (OR = 1.4), psoriasis (OR = 1.4), spider veins (OR = 1.1), and hemangioma (OR = 1.1).CONCLUSIONS: Rosacea is a common skin condition that is most prevalent above the age of 65 years. Rosacea patients have an increased risk for associated comorbidities. Therefore, the diagnostic and therapeutic process for rosacea patients must ensure an integrated, complete dermatological approach in terms of medical care.

KW - Acne Vulgaris/epidemiology

KW - Dermatitis, Seborrheic/diagnosis

KW - Female

KW - Humans

KW - Male

KW - Psoriasis/epidemiology

KW - Rosacea/epidemiology

KW - Skin

KW - Telangiectasis/epidemiology

U2 - 10.1111/ijd.15989

DO - 10.1111/ijd.15989

M3 - SCORING: Journal article

C2 - 34897653

VL - 61

SP - 570

EP - 576

JO - INT J DERMATOL

JF - INT J DERMATOL

SN - 0011-9059

IS - 5

ER -