EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals

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EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals. / Pilz, Micha J; Gamper, Eva-Maria; Efficace, Fabio; Arraras, Juan I; Nolte, Sandra; Liegl, Gregor; Rose, Matthias; Giesinger, Johannes M; EORTC Quality of Life Group.

In: BMC PUBLIC HEALTH, Vol. 22, No. 1, 1040, 24.05.2022.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Pilz, MJ, Gamper, E-M, Efficace, F, Arraras, JI, Nolte, S, Liegl, G, Rose, M, Giesinger, JM & EORTC Quality of Life Group 2022, 'EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals', BMC PUBLIC HEALTH, vol. 22, no. 1, 1040. https://doi.org/10.1186/s12889-022-13211-y

APA

Pilz, M. J., Gamper, E-M., Efficace, F., Arraras, J. I., Nolte, S., Liegl, G., Rose, M., Giesinger, J. M., & EORTC Quality of Life Group (2022). EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals. BMC PUBLIC HEALTH, 22(1), [1040]. https://doi.org/10.1186/s12889-022-13211-y

Vancouver

Bibtex

@article{8adcb2876098452fbe6efe71d12cf739,
title = "EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals",
abstract = "BACKGROUND: General population normative values for the widely used health-related quality of life (HRQoL) measure, European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30), are available for a range of countries. These are mostly countries in northern Europe. However, there is still a lack of such normative values for southern Europe. Therefore, this study aims to provide sex-, age- and health condition-specific normative values for the general Italian population for the EORTC QLQ-C30.MATERIAL AND METHODS: This study is based on Italian EORTC QLQ-C30 general population data previously collected in an international EORTC project comprising over 15,000 respondents across 15 countries. Recruitment and assessment were carried out via online panels. Quota sampling was used for sex and age groups (18‍-‍39, 40-49, 50-59, 60-69 and ≥ 70 years), separately for each country. We applied weights to match the age and sex distribution in our sample with UN statistics for Italy. Along with descriptive statistics, linear regression models were estimated to describe the associations of sex, age and health condition with the EORTC QLQ-C30 scores.RESULTS: A total of 1,036 respondents from Italy were included in our analyses. The weighted mean age was 49.3 years, and 536 (51.7%) participants were female. Having at least one health condition was reported by 60.7% of the participants. Men reported better scores than women on all EORTC QLQ-C30 scales but diarrhoea. While the impact of age differed across scales, older age was overall associated with better HRQoL as shown by the summary score. For all scales, differences were in favour of participants who did not report any health condition, compared to those who reported at least one.CONCLUSION: The Italian normative values for the EORTC QLQ-C30 scales support the interpretation of HRQoL profiles in Italian cancer populations. The strong impact of health conditions on EORTC QLQ-C30 scores highlights the importance of adjusting for the impact of comorbidities in cancer patients when interpreting HRQoL data.",
keywords = "Aged, Female, Humans, Italy/epidemiology, Male, Middle Aged, Neoplasms/epidemiology, Quality of Life, Sex Distribution, Surveys and Questionnaires",
author = "Pilz, {Micha J} and Eva-Maria Gamper and Fabio Efficace and Arraras, {Juan I} and Sandra Nolte and Gregor Liegl and Matthias Rose and Giesinger, {Johannes M} and {EORTC Quality of Life Group}",
note = "{\textcopyright} 2022. The Author(s).",
year = "2022",
month = may,
day = "24",
doi = "10.1186/s12889-022-13211-y",
language = "English",
volume = "22",
journal = "BMC PUBLIC HEALTH",
issn = "1471-2458",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals

AU - Pilz, Micha J

AU - Gamper, Eva-Maria

AU - Efficace, Fabio

AU - Arraras, Juan I

AU - Nolte, Sandra

AU - Liegl, Gregor

AU - Rose, Matthias

AU - Giesinger, Johannes M

AU - EORTC Quality of Life Group

N1 - © 2022. The Author(s).

PY - 2022/5/24

Y1 - 2022/5/24

N2 - BACKGROUND: General population normative values for the widely used health-related quality of life (HRQoL) measure, European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30), are available for a range of countries. These are mostly countries in northern Europe. However, there is still a lack of such normative values for southern Europe. Therefore, this study aims to provide sex-, age- and health condition-specific normative values for the general Italian population for the EORTC QLQ-C30.MATERIAL AND METHODS: This study is based on Italian EORTC QLQ-C30 general population data previously collected in an international EORTC project comprising over 15,000 respondents across 15 countries. Recruitment and assessment were carried out via online panels. Quota sampling was used for sex and age groups (18‍-‍39, 40-49, 50-59, 60-69 and ≥ 70 years), separately for each country. We applied weights to match the age and sex distribution in our sample with UN statistics for Italy. Along with descriptive statistics, linear regression models were estimated to describe the associations of sex, age and health condition with the EORTC QLQ-C30 scores.RESULTS: A total of 1,036 respondents from Italy were included in our analyses. The weighted mean age was 49.3 years, and 536 (51.7%) participants were female. Having at least one health condition was reported by 60.7% of the participants. Men reported better scores than women on all EORTC QLQ-C30 scales but diarrhoea. While the impact of age differed across scales, older age was overall associated with better HRQoL as shown by the summary score. For all scales, differences were in favour of participants who did not report any health condition, compared to those who reported at least one.CONCLUSION: The Italian normative values for the EORTC QLQ-C30 scales support the interpretation of HRQoL profiles in Italian cancer populations. The strong impact of health conditions on EORTC QLQ-C30 scores highlights the importance of adjusting for the impact of comorbidities in cancer patients when interpreting HRQoL data.

AB - BACKGROUND: General population normative values for the widely used health-related quality of life (HRQoL) measure, European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30), are available for a range of countries. These are mostly countries in northern Europe. However, there is still a lack of such normative values for southern Europe. Therefore, this study aims to provide sex-, age- and health condition-specific normative values for the general Italian population for the EORTC QLQ-C30.MATERIAL AND METHODS: This study is based on Italian EORTC QLQ-C30 general population data previously collected in an international EORTC project comprising over 15,000 respondents across 15 countries. Recruitment and assessment were carried out via online panels. Quota sampling was used for sex and age groups (18‍-‍39, 40-49, 50-59, 60-69 and ≥ 70 years), separately for each country. We applied weights to match the age and sex distribution in our sample with UN statistics for Italy. Along with descriptive statistics, linear regression models were estimated to describe the associations of sex, age and health condition with the EORTC QLQ-C30 scores.RESULTS: A total of 1,036 respondents from Italy were included in our analyses. The weighted mean age was 49.3 years, and 536 (51.7%) participants were female. Having at least one health condition was reported by 60.7% of the participants. Men reported better scores than women on all EORTC QLQ-C30 scales but diarrhoea. While the impact of age differed across scales, older age was overall associated with better HRQoL as shown by the summary score. For all scales, differences were in favour of participants who did not report any health condition, compared to those who reported at least one.CONCLUSION: The Italian normative values for the EORTC QLQ-C30 scales support the interpretation of HRQoL profiles in Italian cancer populations. The strong impact of health conditions on EORTC QLQ-C30 scores highlights the importance of adjusting for the impact of comorbidities in cancer patients when interpreting HRQoL data.

KW - Aged

KW - Female

KW - Humans

KW - Italy/epidemiology

KW - Male

KW - Middle Aged

KW - Neoplasms/epidemiology

KW - Quality of Life

KW - Sex Distribution

KW - Surveys and Questionnaires

U2 - 10.1186/s12889-022-13211-y

DO - 10.1186/s12889-022-13211-y

M3 - SCORING: Journal article

C2 - 35610611

VL - 22

JO - BMC PUBLIC HEALTH

JF - BMC PUBLIC HEALTH

SN - 1471-2458

IS - 1

M1 - 1040

ER -