Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green

Standard

Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green : preliminary results. / Betz, C S; Zhorzel, S; Schachenmayr, H; Stepp, H; Havel, M; Siedek, V; Leunig, A; Matthias, C; Hopper, C; Harreus, U.

In: J PLAST RECONSTR AES, Vol. 62, No. 12, 12.2009, p. 1602-8.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Betz, CS, Zhorzel, S, Schachenmayr, H, Stepp, H, Havel, M, Siedek, V, Leunig, A, Matthias, C, Hopper, C & Harreus, U 2009, 'Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green: preliminary results', J PLAST RECONSTR AES, vol. 62, no. 12, pp. 1602-8. https://doi.org/10.1016/j.bjps.2008.07.042

APA

Betz, C. S., Zhorzel, S., Schachenmayr, H., Stepp, H., Havel, M., Siedek, V., Leunig, A., Matthias, C., Hopper, C., & Harreus, U. (2009). Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green: preliminary results. J PLAST RECONSTR AES, 62(12), 1602-8. https://doi.org/10.1016/j.bjps.2008.07.042

Vancouver

Bibtex

@article{cd045b9bf0664d8c8722ac3a5656f21c,
title = "Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green: preliminary results",
abstract = "BACKGROUND: Free-tissue transfer has become a standard procedure for reconstructive surgery in the head and neck area. Flap failures are relatively rare (METHODS: So far, 11 patients with free-flap reconstructions of the upper aerodigestive tract (UADT) have participated in this study. Each participant underwent three endoscopic ICG angiographies (24h intra-operatively and 72h postoperatively). The data obtained were evaluated online as well as offline on a personal computer (PC), and the results compared to the clinical outcome.RESULTS: There were no partial or complete flap losses. One flap was successfully salvaged following initial arterial kinking with impeded perfusion. The ICG fluorescence angiography was tolerated well in all patients. The free flaps showed a delayed yet equal ICG fluorescence as compared to the surrounding tissue. The timing and slope of fluorescence build-up were dependent on circulatory factors. The relative fluorescence maxima of flap versus surrounding were 33% in the initially failing flap and >or=64% for all other examinations.CONCLUSIONS: It was possible to prove the feasibility of endoscopic ICG fluorescence angiography in patients undergoing free-flap transfer to the UADT. The method provides instant information about the perfusion state of the tissue and is easily performed without greater patient discomfort or risk of side effects. Due to the endoscopic approach, the method seems highly promising for this indication and merits further evaluation.",
keywords = "Aged, Coloring Agents, Endoscopy, Feasibility Studies, Female, Fluorescein Angiography, Graft Rejection, Head and Neck Neoplasms, Humans, Indocyanine Green, Male, Microcirculation, Middle Aged, Postoperative Care, Reconstructive Surgical Procedures, Surgical Flaps, Evaluation Studies, Journal Article, Research Support, Non-U.S. Gov't",
author = "Betz, {C S} and S Zhorzel and H Schachenmayr and H Stepp and M Havel and V Siedek and A Leunig and C Matthias and C Hopper and U Harreus",
year = "2009",
month = dec,
doi = "10.1016/j.bjps.2008.07.042",
language = "English",
volume = "62",
pages = "1602--8",
journal = "J PLAST RECONSTR AES",
issn = "1748-6815",
publisher = "Churchill Livingstone",
number = "12",

}

RIS

TY - JOUR

T1 - Endoscopic measurements of free-flap perfusion in the head and neck region using red-excited Indocyanine Green

T2 - preliminary results

AU - Betz, C S

AU - Zhorzel, S

AU - Schachenmayr, H

AU - Stepp, H

AU - Havel, M

AU - Siedek, V

AU - Leunig, A

AU - Matthias, C

AU - Hopper, C

AU - Harreus, U

PY - 2009/12

Y1 - 2009/12

N2 - BACKGROUND: Free-tissue transfer has become a standard procedure for reconstructive surgery in the head and neck area. Flap failures are relatively rare (METHODS: So far, 11 patients with free-flap reconstructions of the upper aerodigestive tract (UADT) have participated in this study. Each participant underwent three endoscopic ICG angiographies (24h intra-operatively and 72h postoperatively). The data obtained were evaluated online as well as offline on a personal computer (PC), and the results compared to the clinical outcome.RESULTS: There were no partial or complete flap losses. One flap was successfully salvaged following initial arterial kinking with impeded perfusion. The ICG fluorescence angiography was tolerated well in all patients. The free flaps showed a delayed yet equal ICG fluorescence as compared to the surrounding tissue. The timing and slope of fluorescence build-up were dependent on circulatory factors. The relative fluorescence maxima of flap versus surrounding were 33% in the initially failing flap and >or=64% for all other examinations.CONCLUSIONS: It was possible to prove the feasibility of endoscopic ICG fluorescence angiography in patients undergoing free-flap transfer to the UADT. The method provides instant information about the perfusion state of the tissue and is easily performed without greater patient discomfort or risk of side effects. Due to the endoscopic approach, the method seems highly promising for this indication and merits further evaluation.

AB - BACKGROUND: Free-tissue transfer has become a standard procedure for reconstructive surgery in the head and neck area. Flap failures are relatively rare (METHODS: So far, 11 patients with free-flap reconstructions of the upper aerodigestive tract (UADT) have participated in this study. Each participant underwent three endoscopic ICG angiographies (24h intra-operatively and 72h postoperatively). The data obtained were evaluated online as well as offline on a personal computer (PC), and the results compared to the clinical outcome.RESULTS: There were no partial or complete flap losses. One flap was successfully salvaged following initial arterial kinking with impeded perfusion. The ICG fluorescence angiography was tolerated well in all patients. The free flaps showed a delayed yet equal ICG fluorescence as compared to the surrounding tissue. The timing and slope of fluorescence build-up were dependent on circulatory factors. The relative fluorescence maxima of flap versus surrounding were 33% in the initially failing flap and >or=64% for all other examinations.CONCLUSIONS: It was possible to prove the feasibility of endoscopic ICG fluorescence angiography in patients undergoing free-flap transfer to the UADT. The method provides instant information about the perfusion state of the tissue and is easily performed without greater patient discomfort or risk of side effects. Due to the endoscopic approach, the method seems highly promising for this indication and merits further evaluation.

KW - Aged

KW - Coloring Agents

KW - Endoscopy

KW - Feasibility Studies

KW - Female

KW - Fluorescein Angiography

KW - Graft Rejection

KW - Head and Neck Neoplasms

KW - Humans

KW - Indocyanine Green

KW - Male

KW - Microcirculation

KW - Middle Aged

KW - Postoperative Care

KW - Reconstructive Surgical Procedures

KW - Surgical Flaps

KW - Evaluation Studies

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.bjps.2008.07.042

DO - 10.1016/j.bjps.2008.07.042

M3 - SCORING: Journal article

C2 - 19036663

VL - 62

SP - 1602

EP - 1608

JO - J PLAST RECONSTR AES

JF - J PLAST RECONSTR AES

SN - 1748-6815

IS - 12

ER -