Emergency localization of radioactive seeds lost during intracoronary brachytherapy
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Emergency localization of radioactive seeds lost during intracoronary brachytherapy. / Krüll, Andreas; Köster, Ralf; Bohuslavizki, Karl Heinz; Todorovic, Manuel; Schmidt, Rainer; Thurmann, Horst; Brockhoff, Carsten; Schwarz, Rudolf; Münzel, Thomas; Alberti, Winfried.
In: CATHETER CARDIO INTE, Vol. 62, No. 4, 08.2004, p. 482-4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Emergency localization of radioactive seeds lost during intracoronary brachytherapy
AU - Krüll, Andreas
AU - Köster, Ralf
AU - Bohuslavizki, Karl Heinz
AU - Todorovic, Manuel
AU - Schmidt, Rainer
AU - Thurmann, Horst
AU - Brockhoff, Carsten
AU - Schwarz, Rudolf
AU - Münzel, Thomas
AU - Alberti, Winfried
N1 - Copyright 2004 Wiley-Liss, Inc.
PY - 2004/8
Y1 - 2004/8
N2 - Recently, it has been reported that brachytherapy catheters ruptured in vivo. Localization of lost beta-radiation-emitting seeds is a problem because no appropriate technique is available that is rapid and precise. We developed a technique to localize beta-emitting seeds utilizing the effect that beta-radiation induces bremsstrahlung. The loss of a single radioactive source was simulated in an Alderson Phantom representing a human body. The beta-induced bremsstrahlung could be detected selectively by a gamma-camera. The position of the radioactive seed could be located within 5 min with an accuracy of +/- 0.5 cm. The result of this study suggests that in an emergency case of loss of a brachytherapy source, a commercially available gamma-camera can be a valuable tool to detect lost beta-radiation-emitting seeds rapidly and precisely. In addition, the technique minimizes the patient's as well as the surgeon's exposure to radiation and reduces the extent of surgical trauma.
AB - Recently, it has been reported that brachytherapy catheters ruptured in vivo. Localization of lost beta-radiation-emitting seeds is a problem because no appropriate technique is available that is rapid and precise. We developed a technique to localize beta-emitting seeds utilizing the effect that beta-radiation induces bremsstrahlung. The loss of a single radioactive source was simulated in an Alderson Phantom representing a human body. The beta-induced bremsstrahlung could be detected selectively by a gamma-camera. The position of the radioactive seed could be located within 5 min with an accuracy of +/- 0.5 cm. The result of this study suggests that in an emergency case of loss of a brachytherapy source, a commercially available gamma-camera can be a valuable tool to detect lost beta-radiation-emitting seeds rapidly and precisely. In addition, the technique minimizes the patient's as well as the surgeon's exposure to radiation and reduces the extent of surgical trauma.
KW - Beta Particles
KW - Brachytherapy/adverse effects
KW - Cardiac Catheterization/adverse effects
KW - Coronary Disease/radiotherapy
KW - Emergency Medical Services
KW - Equipment Failure
KW - Gamma Cameras
KW - Humans
KW - Phantoms, Imaging
KW - Radiation Injuries/etiology
KW - Radiographic Image Interpretation, Computer-Assisted
KW - Strontium Radioisotopes
KW - Time Factors
KW - Yttrium Radioisotopes
U2 - 10.1002/ccd.20086
DO - 10.1002/ccd.20086
M3 - SCORING: Journal article
C2 - 15274158
VL - 62
SP - 482
EP - 484
JO - CATHETER CARDIO INTE
JF - CATHETER CARDIO INTE
SN - 1522-1946
IS - 4
ER -
