Elevated pretreatment serum concentration of YKL-40-An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer.
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Elevated pretreatment serum concentration of YKL-40-An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer. / Thoem, Ina; Andritzky, Birte; Schuch, Gunter; Burkholder, Iris; Edler, Lutz; Johansen, Julia S; Bokemeyer, Carsten; Schumacher, Udo; Laack, Heinz-Eckart.
In: CANCER-AM CANCER SOC, Vol. 116, No. 17, 17, 2010, p. 4114-4121.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Elevated pretreatment serum concentration of YKL-40-An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer.
AU - Thoem, Ina
AU - Andritzky, Birte
AU - Schuch, Gunter
AU - Burkholder, Iris
AU - Edler, Lutz
AU - Johansen, Julia S
AU - Bokemeyer, Carsten
AU - Schumacher, Udo
AU - Laack, Heinz-Eckart
PY - 2010
Y1 - 2010
N2 - The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several cancer types. However, the role of YKL-40 has not been established in nonsmall cell lung cancer (NSCLC).
AB - The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several cancer types. However, the role of YKL-40 has not been established in nonsmall cell lung cancer (NSCLC).
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Tumor Markers, Biological blood
KW - Prognosis
KW - Disease-Free Survival
KW - Neoplasm Metastasis
KW - Carcinoma, Non-Small-Cell Lung blood
KW - Glycoproteins blood
KW - Lectins blood
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Tumor Markers, Biological blood
KW - Prognosis
KW - Disease-Free Survival
KW - Neoplasm Metastasis
KW - Carcinoma, Non-Small-Cell Lung blood
KW - Glycoproteins blood
KW - Lectins blood
M3 - SCORING: Zeitschriftenaufsatz
VL - 116
SP - 4114
EP - 4121
JO - CANCER-AM CANCER SOC
JF - CANCER-AM CANCER SOC
SN - 0008-543X
IS - 17
M1 - 17
ER -