Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device

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Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device. / von Gladiss, Anselm; Graeser, Matthias; Behrends, André; Chen, Xin; Buzug, Thorsten M.

In: SCI REP-UK, Vol. 10, No. 1, 28.10.2020, p. 18432.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{cfb894fa0fcb4fd387dcdce10642ac4e,
title = "Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device",
abstract = "Image reconstruction in magnetic particle imaging is often performed using a system matrix based approach. The acquisition of a system matrix is a time-consuming calibration which may take several weeks and thus, is not feasible for a clinical device. Due to hardware characteristics of the receive chain, a system matrix may not even be used in similar devices but has to be acquired for each imager. In this work, a dedicated device is used for measuring a hybrid system matrix. It is shown that the measurement time of a 3D system matrix is reduced by 96%. The transfer function of the receive chains is measured, which allows the use of the same system matrix in multiple devices. Equivalent image reconstruction results are reached using the hybrid system matrix. Furthermore, the inhomogeneous sensitivity profile of receive coils is successfully applied to a hybrid system matrix. It is shown that each aspect of signal acquisition in magnetic particle imaging can be taken into account using hybrid system matrices. It is favourable to use a hybrid system matrix for image reconstruction in terms of measurement time, signal-to-noise ratio and discretisation.",
author = "{von Gladiss}, Anselm and Matthias Graeser and Andr{\'e} Behrends and Xin Chen and Buzug, {Thorsten M}",
year = "2020",
month = oct,
day = "28",
doi = "10.1038/s41598-020-75122-5",
language = "English",
volume = "10",
pages = "18432",
journal = "SCI REP-UK",
issn = "2045-2322",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device

AU - von Gladiss, Anselm

AU - Graeser, Matthias

AU - Behrends, André

AU - Chen, Xin

AU - Buzug, Thorsten M

PY - 2020/10/28

Y1 - 2020/10/28

N2 - Image reconstruction in magnetic particle imaging is often performed using a system matrix based approach. The acquisition of a system matrix is a time-consuming calibration which may take several weeks and thus, is not feasible for a clinical device. Due to hardware characteristics of the receive chain, a system matrix may not even be used in similar devices but has to be acquired for each imager. In this work, a dedicated device is used for measuring a hybrid system matrix. It is shown that the measurement time of a 3D system matrix is reduced by 96%. The transfer function of the receive chains is measured, which allows the use of the same system matrix in multiple devices. Equivalent image reconstruction results are reached using the hybrid system matrix. Furthermore, the inhomogeneous sensitivity profile of receive coils is successfully applied to a hybrid system matrix. It is shown that each aspect of signal acquisition in magnetic particle imaging can be taken into account using hybrid system matrices. It is favourable to use a hybrid system matrix for image reconstruction in terms of measurement time, signal-to-noise ratio and discretisation.

AB - Image reconstruction in magnetic particle imaging is often performed using a system matrix based approach. The acquisition of a system matrix is a time-consuming calibration which may take several weeks and thus, is not feasible for a clinical device. Due to hardware characteristics of the receive chain, a system matrix may not even be used in similar devices but has to be acquired for each imager. In this work, a dedicated device is used for measuring a hybrid system matrix. It is shown that the measurement time of a 3D system matrix is reduced by 96%. The transfer function of the receive chains is measured, which allows the use of the same system matrix in multiple devices. Equivalent image reconstruction results are reached using the hybrid system matrix. Furthermore, the inhomogeneous sensitivity profile of receive coils is successfully applied to a hybrid system matrix. It is shown that each aspect of signal acquisition in magnetic particle imaging can be taken into account using hybrid system matrices. It is favourable to use a hybrid system matrix for image reconstruction in terms of measurement time, signal-to-noise ratio and discretisation.

U2 - 10.1038/s41598-020-75122-5

DO - 10.1038/s41598-020-75122-5

M3 - SCORING: Journal article

C2 - 33116183

VL - 10

SP - 18432

JO - SCI REP-UK

JF - SCI REP-UK

SN - 2045-2322

IS - 1

ER -