Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.

  • Stefan Zeuzem
  • Tarik Asselah
  • Peter Angus
  • Jean-Pierre Zarski
  • Dominique Larrey
  • Beat Müllhaupt
  • Ed Gane
  • Marcus Schuchmann
  • Ansgar W. Lohse
  • Stanislas Pol
  • Jean-Pierre Bronowicki
  • Stuart Roberts
  • Keikawus Arasteh
  • Fabien Zoulim
  • Markus Heim
  • Jerry O Stern
  • George Kukolj
  • Gerhard Nehmiz
  • Carla Haefner
  • Wulf Otto Boecher

Related Research units

Abstract

Therapeutic regimens are being developed for patients with hepatitis C virus (HCV) infection that do not include the combination of peginterferon alfa and ribavirin. We investigated the antiviral effect and safety of BI 201335 (an inhibitor of the NS3/4A protease) and BI 207127 (an inhibitor of the NS5B non-nucleoside polymerase) with ribavirin.

Bibliographical data

Original languageEnglish
Article number6
ISSN0016-5085
Publication statusPublished - 2011
pubmed 21925126