Research ExplorerPublicationsEfficacy of ivermectin mass-drug administration to control s...

Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016

Standard

Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016. / Beeres, Dorien T; Ravensbergen, Sofanne J; Heidema, Annelies; Cornish, Darren; Vonk, Machiel; Wijnholds, Leonie D; Hendriks, Jessica J H; Kleinnijenhuis, Johanneke; Omansen, Till F.; Stienstra, Ymkje.

In: PLOS NEGLECT TROP D, Vol. 12, No. 5, 05.2018, p. e0006401.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Beeres, DT, Ravensbergen, SJ, Heidema, A, Cornish, D, Vonk, M, Wijnholds, LD, Hendriks, JJH, Kleinnijenhuis, J, Omansen, TF & Stienstra, Y 2018, 'Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016', PLOS NEGLECT TROP D, vol. 12, no. 5, pp. e0006401. https://doi.org/10.1371/journal.pntd.0006401

APA

Beeres, D. T., Ravensbergen, S. J., Heidema, A., Cornish, D., Vonk, M., Wijnholds, L. D., Hendriks, J. J. H., Kleinnijenhuis, J., Omansen, T. F., & Stienstra, Y. (2018). Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016. PLOS NEGLECT TROP D, 12(5), e0006401. https://doi.org/10.1371/journal.pntd.0006401

Vancouver

Beeres DT, Ravensbergen SJ, Heidema A, Cornish D, Vonk M, Wijnholds LD et al. Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016. PLOS NEGLECT TROP D. 2018 May;12(5):e0006401. https://doi.org/10.1371/journal.pntd.0006401

Bibtex

@article{5d7e4e8205344775890e2e15f1a355bd,
title = "Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016",
abstract = "Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands. On arrival, all asylum seekers from Eritrea or Ethiopia were checked for clinical scabies signs and received ivermectin/permethrin either as prevention or treatment. A retrospective cohort study was conducted to compare the reinfestations and complications of scabies in asylum seekers who entered the Netherlands before and during the intervention and who received ivermectin/permethrin. In total, 2866 asylum seekers received treatment during the study period (January 2014 -March 2016) of which 1359 (47.4%) had clinical signs of scabies. During the programme, most of the asylum seekers with scabies were already diagnosed on arrival as part of the SIP screening (580 (64.7%) of the 897). Asylum seekers with more than one scabies episode reduced from 42.0% (194/462) before the programme to 27.2% (243/897) during the programme (RR = 0.64, 95% CI = 0.55-0.75). Development of scabies complications later in the asylum procedure reduced from 12.3% (57/462) to 4.6% (41/897). A scabies prevention and treatment programme at start of the asylum procedure was feasible and effective in the Netherlands; patients were diagnosed early and risk of reinfestations and complications reduced. To achieve a further decrease of scabies, implementation of the programme in multiple asylum centres may be needed.",
keywords = "Acaricides/administration & dosage, Adolescent, Adult, Animals, Female, Humans, Ivermectin/administration & dosage, Male, Middle Aged, Netherlands, Refugees/statistics & numerical data, Retrospective Studies, Sarcoptes scabiei/drug effects, Scabies/drug therapy, Young Adult",
author = "Beeres, {Dorien T} and Ravensbergen, {Sofanne J} and Annelies Heidema and Darren Cornish and Machiel Vonk and Wijnholds, {Leonie D} and Hendriks, {Jessica J H} and Johanneke Kleinnijenhuis and Omansen, {Till F.} and Ymkje Stienstra",
year = "2018",
month = may,
doi = "10.1371/journal.pntd.0006401",
language = "English",
volume = "12",
pages = "e0006401",
journal = "PLOS NEGLECT TROP D",
issn = "1935-2735",
publisher = "Public Library of Science",
number = "5",

}

RIS

TY - JOUR

T1 - Efficacy of ivermectin mass-drug administration to control scabies in asylum seekers in the Netherlands: A retrospective cohort study between January 2014 - March 2016

AU - Beeres, Dorien T

AU - Ravensbergen, Sofanne J

AU - Heidema, Annelies

AU - Cornish, Darren

AU - Vonk, Machiel

AU - Wijnholds, Leonie D

AU - Hendriks, Jessica J H

AU - Kleinnijenhuis, Johanneke

AU - Omansen, Till F.

AU - Stienstra, Ymkje

PY - 2018/5

Y1 - 2018/5

N2 - Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands. On arrival, all asylum seekers from Eritrea or Ethiopia were checked for clinical scabies signs and received ivermectin/permethrin either as prevention or treatment. A retrospective cohort study was conducted to compare the reinfestations and complications of scabies in asylum seekers who entered the Netherlands before and during the intervention and who received ivermectin/permethrin. In total, 2866 asylum seekers received treatment during the study period (January 2014 -March 2016) of which 1359 (47.4%) had clinical signs of scabies. During the programme, most of the asylum seekers with scabies were already diagnosed on arrival as part of the SIP screening (580 (64.7%) of the 897). Asylum seekers with more than one scabies episode reduced from 42.0% (194/462) before the programme to 27.2% (243/897) during the programme (RR = 0.64, 95% CI = 0.55-0.75). Development of scabies complications later in the asylum procedure reduced from 12.3% (57/462) to 4.6% (41/897). A scabies prevention and treatment programme at start of the asylum procedure was feasible and effective in the Netherlands; patients were diagnosed early and risk of reinfestations and complications reduced. To achieve a further decrease of scabies, implementation of the programme in multiple asylum centres may be needed.

AB - Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands. On arrival, all asylum seekers from Eritrea or Ethiopia were checked for clinical scabies signs and received ivermectin/permethrin either as prevention or treatment. A retrospective cohort study was conducted to compare the reinfestations and complications of scabies in asylum seekers who entered the Netherlands before and during the intervention and who received ivermectin/permethrin. In total, 2866 asylum seekers received treatment during the study period (January 2014 -March 2016) of which 1359 (47.4%) had clinical signs of scabies. During the programme, most of the asylum seekers with scabies were already diagnosed on arrival as part of the SIP screening (580 (64.7%) of the 897). Asylum seekers with more than one scabies episode reduced from 42.0% (194/462) before the programme to 27.2% (243/897) during the programme (RR = 0.64, 95% CI = 0.55-0.75). Development of scabies complications later in the asylum procedure reduced from 12.3% (57/462) to 4.6% (41/897). A scabies prevention and treatment programme at start of the asylum procedure was feasible and effective in the Netherlands; patients were diagnosed early and risk of reinfestations and complications reduced. To achieve a further decrease of scabies, implementation of the programme in multiple asylum centres may be needed.

KW - Acaricides/administration & dosage

KW - Adolescent

KW - Adult

KW - Animals

KW - Female

KW - Humans

KW - Ivermectin/administration & dosage

KW - Male

KW - Middle Aged

KW - Netherlands

KW - Refugees/statistics & numerical data

KW - Retrospective Studies

KW - Sarcoptes scabiei/drug effects

KW - Scabies/drug therapy

KW - Young Adult

U2 - 10.1371/journal.pntd.0006401

DO - 10.1371/journal.pntd.0006401

M3 - SCORING: Journal article

C2 - 29771941

VL - 12

SP - e0006401

JO - PLOS NEGLECT TROP D

JF - PLOS NEGLECT TROP D

SN - 1935-2735

IS - 5

ER -