Effects of chronic lithium, clorgyline, imipramine, fluphenazine and constant darkness on the alpha-melanotropin content and circadian rhythm in rat brain.
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Effects of chronic lithium, clorgyline, imipramine, fluphenazine and constant darkness on the alpha-melanotropin content and circadian rhythm in rat brain. / O'Donohue, T L; Wirz-Justice, A; Kafka, M S; Naber, Dieter; Campbell, I C; Wehr, T A.
In: EUR J PHARMACOL, Vol. 85, No. 1, 1, 1982, p. 1-7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Effects of chronic lithium, clorgyline, imipramine, fluphenazine and constant darkness on the alpha-melanotropin content and circadian rhythm in rat brain.
AU - O'Donohue, T L
AU - Wirz-Justice, A
AU - Kafka, M S
AU - Naber, Dieter
AU - Campbell, I C
AU - Wehr, T A
PY - 1982
Y1 - 1982
N2 - The effects of constant darkness, chronic lithium, clorgyline, imipramine and fluphenazine treatment on the content and diurnal rhythm of alpha-MSH in rat forebrain were investigated. The persistence of the alpha-MSH rhythm in constant darkness demonstrated that the rhythm was circadian in nature. Constant darkness increased the 24 h mean alpha-MSH concentration in brain while lithium, fluphenazine and imipramine decreased it. In addition, imipramine and clorgyline delayed the phase of the alpha-MSH circadian rhythm while lithium advanced it.
AB - The effects of constant darkness, chronic lithium, clorgyline, imipramine and fluphenazine treatment on the content and diurnal rhythm of alpha-MSH in rat forebrain were investigated. The persistence of the alpha-MSH rhythm in constant darkness demonstrated that the rhythm was circadian in nature. Constant darkness increased the 24 h mean alpha-MSH concentration in brain while lithium, fluphenazine and imipramine decreased it. In addition, imipramine and clorgyline delayed the phase of the alpha-MSH circadian rhythm while lithium advanced it.
M3 - SCORING: Zeitschriftenaufsatz
VL - 85
SP - 1
EP - 7
JO - EUR J PHARMACOL
JF - EUR J PHARMACOL
SN - 0014-2999
IS - 1
M1 - 1
ER -