Effects of brain polarization on reaction times and pinch force in chronic stroke.
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Effects of brain polarization on reaction times and pinch force in chronic stroke. / Hummel, Friedhelm; Voller, Bernhard; Celnik, Pablo; Floel, Agnes; Giraux, Pascal; Gerloff, Christian; Cohen, Leonardo G.
In: BMC NEUROSCI, Vol. 7, 2006, p. 73.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Effects of brain polarization on reaction times and pinch force in chronic stroke.
AU - Hummel, Friedhelm
AU - Voller, Bernhard
AU - Celnik, Pablo
AU - Floel, Agnes
AU - Giraux, Pascal
AU - Gerloff, Christian
AU - Cohen, Leonardo G
PY - 2006
Y1 - 2006
N2 - BACKGROUND: Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively simpler motor tasks are similarly affected. Here we tested the effects of tDCS on pinch force (PF) and simple reaction time (RT) tasks in patients with chronic stroke in a double-blind cross-over Sham-controlled experimental design. RESULTS: Anodal tDCS shortened reaction times and improved pinch force in the paretic hand relative to Sham stimulation, an effect present in patients with higher impairment. CONCLUSION: tDCS of M1affected hemisphere can modulate performance of motor tasks simpler than those previously studied, a finding that could potentially benefit patients with relatively higher impairment levels.
AB - BACKGROUND: Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively simpler motor tasks are similarly affected. Here we tested the effects of tDCS on pinch force (PF) and simple reaction time (RT) tasks in patients with chronic stroke in a double-blind cross-over Sham-controlled experimental design. RESULTS: Anodal tDCS shortened reaction times and improved pinch force in the paretic hand relative to Sham stimulation, an effect present in patients with higher impairment. CONCLUSION: tDCS of M1affected hemisphere can modulate performance of motor tasks simpler than those previously studied, a finding that could potentially benefit patients with relatively higher impairment levels.
U2 - 10.1186/1471-2202-7-73
DO - 10.1186/1471-2202-7-73
M3 - SCORING: Zeitschriftenaufsatz
VL - 7
SP - 73
JO - BMC NEUROSCI
JF - BMC NEUROSCI
SN - 1471-2202
ER -