Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review

Bryant J Jongkees; Bernhard Hommel; Simone Kühn; Lorenza S Colzato

doi:10.1016/j.jpsychires.2015.08.014

Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review

Standard

Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review. / Jongkees, Bryant J; Hommel, Bernhard; Kühn, Simone; Colzato, Lorenza S.

In: J PSYCHIATR RES, Vol. 70, 11.2015, p. 50-7.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jongkees, BJ, Hommel, B, Kühn, S & Colzato, LS 2015, 'Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review', J PSYCHIATR RES, vol. 70, pp. 50-7. https://doi.org/10.1016/j.jpsychires.2015.08.014

APA

Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review. J PSYCHIATR RES, 70, 50-7. https://doi.org/10.1016/j.jpsychires.2015.08.014

Vancouver

Jongkees BJ, Hommel B, Kühn S, Colzato LS. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review. J PSYCHIATR RES. 2015 Nov;70:50-7. https://doi.org/10.1016/j.jpsychires.2015.08.014

Bibtex

@article{248521eb47774f75bae93884caa321fc,

title = "Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review",

abstract = "Consuming the amino-acid tyrosine (TYR), the precursor of dopamine (DA) and norepinephrine (NE), may counteract decrements in neurotransmitter function and cognitive performance. However, reports on the effectiveness of TYR supplementation vary considerably, with some studies finding beneficial effects, whereas others do not. Here we review the available cognitive/behavioral studies on TYR, to elucidate whether and when TYR supplementation can be beneficial for performance. The potential of using TYR supplementation to treat clinical disorders seems limited and its benefits are likely determined by the presence and extent of impaired neurotransmitter function and synthesis. Likewise, the potential of TYR supplementation for enhancing physical exercise seems minimal as well, perhaps because the link between physical exercise and catecholamine function is mediated by many other factors. In contrast, TYR does seem to effectively enhance cognitive performance, particularly in short-term stressful and/or cognitively demanding situations. We conclude that TYR is an effective enhancer of cognition, but only when neurotransmitter function is intact and DA and/or NE is temporarily depleted.",

author = "Jongkees, {Bryant J} and Bernhard Hommel and Simone K{\"u}hn and Colzato, {Lorenza S}",

year = "2015",

month = nov,

doi = "10.1016/j.jpsychires.2015.08.014",

language = "English",

volume = "70",

pages = "50--7",

journal = "J PSYCHIATR RES",

issn = "0022-3956",

publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands-A review

AU - Jongkees, Bryant J

AU - Hommel, Bernhard

AU - Kühn, Simone

AU - Colzato, Lorenza S

PY - 2015/11

Y1 - 2015/11

N2 - Consuming the amino-acid tyrosine (TYR), the precursor of dopamine (DA) and norepinephrine (NE), may counteract decrements in neurotransmitter function and cognitive performance. However, reports on the effectiveness of TYR supplementation vary considerably, with some studies finding beneficial effects, whereas others do not. Here we review the available cognitive/behavioral studies on TYR, to elucidate whether and when TYR supplementation can be beneficial for performance. The potential of using TYR supplementation to treat clinical disorders seems limited and its benefits are likely determined by the presence and extent of impaired neurotransmitter function and synthesis. Likewise, the potential of TYR supplementation for enhancing physical exercise seems minimal as well, perhaps because the link between physical exercise and catecholamine function is mediated by many other factors. In contrast, TYR does seem to effectively enhance cognitive performance, particularly in short-term stressful and/or cognitively demanding situations. We conclude that TYR is an effective enhancer of cognition, but only when neurotransmitter function is intact and DA and/or NE is temporarily depleted.

AB - Consuming the amino-acid tyrosine (TYR), the precursor of dopamine (DA) and norepinephrine (NE), may counteract decrements in neurotransmitter function and cognitive performance. However, reports on the effectiveness of TYR supplementation vary considerably, with some studies finding beneficial effects, whereas others do not. Here we review the available cognitive/behavioral studies on TYR, to elucidate whether and when TYR supplementation can be beneficial for performance. The potential of using TYR supplementation to treat clinical disorders seems limited and its benefits are likely determined by the presence and extent of impaired neurotransmitter function and synthesis. Likewise, the potential of TYR supplementation for enhancing physical exercise seems minimal as well, perhaps because the link between physical exercise and catecholamine function is mediated by many other factors. In contrast, TYR does seem to effectively enhance cognitive performance, particularly in short-term stressful and/or cognitively demanding situations. We conclude that TYR is an effective enhancer of cognition, but only when neurotransmitter function is intact and DA and/or NE is temporarily depleted.

U2 - 10.1016/j.jpsychires.2015.08.014

DO - 10.1016/j.jpsychires.2015.08.014

M3 - SCORING: Journal article

C2 - 26424423

VL - 70

SP - 50

EP - 57

JO - J PSYCHIATR RES

JF - J PSYCHIATR RES

SN - 0022-3956

ER -