Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms.

Dieter Naber; C Finkbeiner; B Fischer; K J Zander; M Ackenheil

Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms.

Standard

Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms. / Naber, Dieter; Finkbeiner, C; Fischer, B; Zander, K J; Ackenheil, M.

In: NEUROPSYCHOBIOLOGY, Vol. 6, No. 4, 4, 1980, p. 181-189.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Naber, D, Finkbeiner, C, Fischer, B, Zander, KJ & Ackenheil, M 1980, 'Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms.', NEUROPSYCHOBIOLOGY, vol. 6, no. 4, 4, pp. 181-189. <http://www.ncbi.nlm.nih.gov/pubmed/6104798?dopt=Citation>

APA

Naber, D., Finkbeiner, C., Fischer, B., Zander, K. J., & Ackenheil, M. (1980). Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms. NEUROPSYCHOBIOLOGY, 6(4), 181-189. [4]. http://www.ncbi.nlm.nih.gov/pubmed/6104798?dopt=Citation

Vancouver

Naber D, Finkbeiner C, Fischer B, Zander KJ, Ackenheil M. Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms. NEUROPSYCHOBIOLOGY. 1980;6(4):181-189. 4.

Bibtex

@article{1a751bdcb6444ac5bc2ccc8feb9ab87d,

title = "Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms.",

abstract = "The estimation of serum prolactin (Prl) and norepinephrine (NE) in chronic schizophrenics treated with neuroleptics for 5-25 years showed no elevated Prl levels in either men or women (4.9 +/- 4.1 and 13.7 +/- 12.1 ng/ml, respectively). No significant correlation to duration or dosage of neuroleptic treatment, psychopathological syndromes and occurrence of tardive dyskinesia or parkinsonian side effects could be seen. The development of tolerance of the tuberoinfundibular dopamine system is discussed. The NE levels were distinctly elevated in both sexes; in men up to 0.77 +/- 0.4 and in women up to 0.90 +/- 0.48 ng/ml. This elevation is induced rather by neuroleptic treatment than by external factors. A significant relationship between dosage or duration of anticholinergic treatment and the severity of tardive dyskinesia was found in men.",

author = "Dieter Naber and C Finkbeiner and B Fischer and Zander, {K J} and M Ackenheil",

year = "1980",

language = "Deutsch",

volume = "6",

pages = "181--189",

journal = "NEUROPSYCHOBIOLOGY",

issn = "0302-282X",

publisher = "S. Karger AG",

number = "4",

}

RIS

TY - JOUR

T1 - Effect of long-term neuroleptic treatment on prolactin and norepinephrine levels in serum of chronic schizophrenics: relations to psychopathology and extrapyramidal symptoms.

AU - Naber, Dieter

AU - Finkbeiner, C

AU - Fischer, B

AU - Zander, K J

AU - Ackenheil, M

PY - 1980

Y1 - 1980

N2 - The estimation of serum prolactin (Prl) and norepinephrine (NE) in chronic schizophrenics treated with neuroleptics for 5-25 years showed no elevated Prl levels in either men or women (4.9 +/- 4.1 and 13.7 +/- 12.1 ng/ml, respectively). No significant correlation to duration or dosage of neuroleptic treatment, psychopathological syndromes and occurrence of tardive dyskinesia or parkinsonian side effects could be seen. The development of tolerance of the tuberoinfundibular dopamine system is discussed. The NE levels were distinctly elevated in both sexes; in men up to 0.77 +/- 0.4 and in women up to 0.90 +/- 0.48 ng/ml. This elevation is induced rather by neuroleptic treatment than by external factors. A significant relationship between dosage or duration of anticholinergic treatment and the severity of tardive dyskinesia was found in men.

AB - The estimation of serum prolactin (Prl) and norepinephrine (NE) in chronic schizophrenics treated with neuroleptics for 5-25 years showed no elevated Prl levels in either men or women (4.9 +/- 4.1 and 13.7 +/- 12.1 ng/ml, respectively). No significant correlation to duration or dosage of neuroleptic treatment, psychopathological syndromes and occurrence of tardive dyskinesia or parkinsonian side effects could be seen. The development of tolerance of the tuberoinfundibular dopamine system is discussed. The NE levels were distinctly elevated in both sexes; in men up to 0.77 +/- 0.4 and in women up to 0.90 +/- 0.48 ng/ml. This elevation is induced rather by neuroleptic treatment than by external factors. A significant relationship between dosage or duration of anticholinergic treatment and the severity of tardive dyskinesia was found in men.

M3 - SCORING: Zeitschriftenaufsatz

VL - 6

SP - 181

EP - 189

JO - NEUROPSYCHOBIOLOGY

JF - NEUROPSYCHOBIOLOGY

SN - 0302-282X

IS - 4

M1 - 4

ER -