Eddy-current compensated diffusion weighting with a single refocusing RF pulse.
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Eddy-current compensated diffusion weighting with a single refocusing RF pulse. / Finsterbusch, Jürgen.
In: MAGN RESON MED, Vol. 61, No. 3, 3, 2009, p. 748-754.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Eddy-current compensated diffusion weighting with a single refocusing RF pulse.
AU - Finsterbusch, Jürgen
PY - 2009
Y1 - 2009
N2 - A modification of the Stejskal-Tanner diffusion-weighting preparation with a single refocusing RF pulse is presented which involves three gradient lobes that can be adjusted to null eddy currents with any given decay rate to reduce geometric distortions in diffusion-weighted echo-planar imaging (EPI). It has a very similar compensation performance as the commonly used double-spin-echo preparation but (i) is less sensitive to flip angle imperfections, e.g. along the slice profile, and B(1) inhomogeneities and (ii) can yield shorter echo times for moderate b values, notably for longer echo trains as required for higher spatial resolution. It therefore can provide an increased signal-to-noise ratio as is simulated numerically and demonstrated experimentally in water phantoms and the human brain for standard EPI (2.0 x 2.0 mm(2)) and high-resolution EPI of inner field-of-views using 2D-selective RF excitations (0.5 x 1.0 mm(2)). Thus, the presented preparation may help to overcome current limitations of diffusion-weighted EPI, in particular at high static magnetic fields.
AB - A modification of the Stejskal-Tanner diffusion-weighting preparation with a single refocusing RF pulse is presented which involves three gradient lobes that can be adjusted to null eddy currents with any given decay rate to reduce geometric distortions in diffusion-weighted echo-planar imaging (EPI). It has a very similar compensation performance as the commonly used double-spin-echo preparation but (i) is less sensitive to flip angle imperfections, e.g. along the slice profile, and B(1) inhomogeneities and (ii) can yield shorter echo times for moderate b values, notably for longer echo trains as required for higher spatial resolution. It therefore can provide an increased signal-to-noise ratio as is simulated numerically and demonstrated experimentally in water phantoms and the human brain for standard EPI (2.0 x 2.0 mm(2)) and high-resolution EPI of inner field-of-views using 2D-selective RF excitations (0.5 x 1.0 mm(2)). Thus, the presented preparation may help to overcome current limitations of diffusion-weighted EPI, in particular at high static magnetic fields.
M3 - SCORING: Zeitschriftenaufsatz
VL - 61
SP - 748
EP - 754
JO - MAGN RESON MED
JF - MAGN RESON MED
SN - 0740-3194
IS - 3
M1 - 3
ER -