Dyspnoea: a multidimensional and multidisciplinary approach

TY - JOUR

T1 - Dyspnoea: a multidimensional and multidisciplinary approach

AU - Laviolette, Louis

AU - Laveneziana, Pierantonio

AU - ERS Research Seminar Faculty

AU - Von Leupoldt, Andreas

N1 - ©ERS 2014.

PY - 2014/6/1

Y1 - 2014/6/1

N2 - Dyspnoea is a debilitating symptom that affects quality of life, exercise tolerance and mortality in various disease conditions/states. In patients with chronic obstructive pulmonary disease (COPD), it has been shown to be a better predictor of mortality than forced expiratory volume in 1 s. In patients with heart disease it is a better predictor of mortality than angina. Dyspnoea is also associated with decreased functional status and worse psychological health in older individuals living at home. It also contributes to the low adherence to exercise training programmes in sedentary adults and in COPD patients. The mechanisms of dyspnoea are still unclear. Recent studies have emphasised the multidimensional nature of dyspnoea in the sensory-perceptual (intensity and quality), affective distress and impact domains. The perception of dyspnoea involves a complex chain of events that depend on varying cortical integration of several afferent/efferent signals and coloured by affective processing. This review, which stems from the European Respiratory Society research symposium held in Paris, France in November 2012, aims to provide state-of-the-art advances on the multidimensional and multidisciplinary aspects of dyspnoea, by addressing three different themes: 1) the neurophysiology of dyspnoea, 2) exercise and dyspnoea, and 3) the clinical impact and management of dyspnoea.

AB - Dyspnoea is a debilitating symptom that affects quality of life, exercise tolerance and mortality in various disease conditions/states. In patients with chronic obstructive pulmonary disease (COPD), it has been shown to be a better predictor of mortality than forced expiratory volume in 1 s. In patients with heart disease it is a better predictor of mortality than angina. Dyspnoea is also associated with decreased functional status and worse psychological health in older individuals living at home. It also contributes to the low adherence to exercise training programmes in sedentary adults and in COPD patients. The mechanisms of dyspnoea are still unclear. Recent studies have emphasised the multidimensional nature of dyspnoea in the sensory-perceptual (intensity and quality), affective distress and impact domains. The perception of dyspnoea involves a complex chain of events that depend on varying cortical integration of several afferent/efferent signals and coloured by affective processing. This review, which stems from the European Respiratory Society research symposium held in Paris, France in November 2012, aims to provide state-of-the-art advances on the multidimensional and multidisciplinary aspects of dyspnoea, by addressing three different themes: 1) the neurophysiology of dyspnoea, 2) exercise and dyspnoea, and 3) the clinical impact and management of dyspnoea.

KW - Congresses as Topic

KW - Dyspnea

KW - Exercise

KW - Exercise Tolerance

KW - France

KW - Health Status

KW - Humans

KW - Pulmonary Disease, Chronic Obstructive

KW - Pulmonary Medicine

KW - Respiration

KW - Treatment Outcome

U2 - 10.1183/09031936.00092613

DO - 10.1183/09031936.00092613

M3 - SCORING: Journal article

C2 - 24525437

VL - 43

SP - 1750

EP - 1762

JO - EUR RESPIR J

JF - EUR RESPIR J

SN - 0903-1936

IS - 6

ER -