Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant

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Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant. / Heinrich, Fabian; Romich, Carina; Zimmermann, Tamara; Kniep, Inga; Fitzek, Antonia; Steurer, Stefan; Glatzel, Markus; Nörz, Dominik; Günther, Thomas; Czech-Sioli, Manja; Fischer, Nicole; Grundhoff, Adam; Lütgehetmann, Marc; Ondruschka, Benjamin.

In: INT J LEGAL MED, Vol. 136, No. 1, 01.2022, p. 193-202.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{e38005bbf596419fb7e8c3d03a1a48c6,
title = "Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant",
abstract = "The current pandemic with Severe acute respiratory syndrome-coronavirus-2 has been taking on new dynamics since the emergence of new variants last fall, some of them spreading more rapidly. Many countries currently find themselves in a race to ramp up vaccination strategies that have been initiated and a possible third wave of the pandemic from new variants, such as the Variant of Concern-202012/01 from the B.1.1.7 lineage. Until today, many investigations in death cases of Coronavirus-disease-19 have been conducted, revealing pulmonary damage to be the predominant feature of the disease. Thereby, different degrees of macroscopic and microscopic lung damage have been reported, most of them resembling an Acute Respiratory Distress Syndrome. Far more, systemic complications of the disease such as pulmonary embolisms have been described. However, neither morphologic nor virologic findings of patients dying of the new variants have yet been reported. Here, we report on a comprehensive analysis of radiologic, morphologic, and virologic findings in a fatal case of this variant.",
author = "Fabian Heinrich and Carina Romich and Tamara Zimmermann and Inga Kniep and Antonia Fitzek and Stefan Steurer and Markus Glatzel and Dominik N{\"o}rz and Thomas G{\"u}nther and Manja Czech-Sioli and Nicole Fischer and Adam Grundhoff and Marc L{\"u}tgehetmann and Benjamin Ondruschka",
year = "2022",
month = jan,
doi = "10.1007/s00414-021-02618-8",
language = "English",
volume = "136",
pages = "193--202",
journal = "INT J LEGAL MED",
issn = "0937-9827",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant

AU - Heinrich, Fabian

AU - Romich, Carina

AU - Zimmermann, Tamara

AU - Kniep, Inga

AU - Fitzek, Antonia

AU - Steurer, Stefan

AU - Glatzel, Markus

AU - Nörz, Dominik

AU - Günther, Thomas

AU - Czech-Sioli, Manja

AU - Fischer, Nicole

AU - Grundhoff, Adam

AU - Lütgehetmann, Marc

AU - Ondruschka, Benjamin

PY - 2022/1

Y1 - 2022/1

N2 - The current pandemic with Severe acute respiratory syndrome-coronavirus-2 has been taking on new dynamics since the emergence of new variants last fall, some of them spreading more rapidly. Many countries currently find themselves in a race to ramp up vaccination strategies that have been initiated and a possible third wave of the pandemic from new variants, such as the Variant of Concern-202012/01 from the B.1.1.7 lineage. Until today, many investigations in death cases of Coronavirus-disease-19 have been conducted, revealing pulmonary damage to be the predominant feature of the disease. Thereby, different degrees of macroscopic and microscopic lung damage have been reported, most of them resembling an Acute Respiratory Distress Syndrome. Far more, systemic complications of the disease such as pulmonary embolisms have been described. However, neither morphologic nor virologic findings of patients dying of the new variants have yet been reported. Here, we report on a comprehensive analysis of radiologic, morphologic, and virologic findings in a fatal case of this variant.

AB - The current pandemic with Severe acute respiratory syndrome-coronavirus-2 has been taking on new dynamics since the emergence of new variants last fall, some of them spreading more rapidly. Many countries currently find themselves in a race to ramp up vaccination strategies that have been initiated and a possible third wave of the pandemic from new variants, such as the Variant of Concern-202012/01 from the B.1.1.7 lineage. Until today, many investigations in death cases of Coronavirus-disease-19 have been conducted, revealing pulmonary damage to be the predominant feature of the disease. Thereby, different degrees of macroscopic and microscopic lung damage have been reported, most of them resembling an Acute Respiratory Distress Syndrome. Far more, systemic complications of the disease such as pulmonary embolisms have been described. However, neither morphologic nor virologic findings of patients dying of the new variants have yet been reported. Here, we report on a comprehensive analysis of radiologic, morphologic, and virologic findings in a fatal case of this variant.

U2 - 10.1007/s00414-021-02618-8

DO - 10.1007/s00414-021-02618-8

M3 - SCORING: Journal article

C2 - 34089348

VL - 136

SP - 193

EP - 202

JO - INT J LEGAL MED

JF - INT J LEGAL MED

SN - 0937-9827

IS - 1

ER -