Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant
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Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant. / Heinrich, Fabian; Romich, Carina; Zimmermann, Tamara; Kniep, Inga; Fitzek, Antonia; Steurer, Stefan; Glatzel, Markus; Nörz, Dominik; Günther, Thomas; Czech-Sioli, Manja; Fischer, Nicole; Grundhoff, Adam; Lütgehetmann, Marc; Ondruschka, Benjamin.
In: INT J LEGAL MED, Vol. 136, No. 1, 01.2022, p. 193-202.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant
AU - Heinrich, Fabian
AU - Romich, Carina
AU - Zimmermann, Tamara
AU - Kniep, Inga
AU - Fitzek, Antonia
AU - Steurer, Stefan
AU - Glatzel, Markus
AU - Nörz, Dominik
AU - Günther, Thomas
AU - Czech-Sioli, Manja
AU - Fischer, Nicole
AU - Grundhoff, Adam
AU - Lütgehetmann, Marc
AU - Ondruschka, Benjamin
PY - 2022/1
Y1 - 2022/1
N2 - The current pandemic with Severe acute respiratory syndrome-coronavirus-2 has been taking on new dynamics since the emergence of new variants last fall, some of them spreading more rapidly. Many countries currently find themselves in a race to ramp up vaccination strategies that have been initiated and a possible third wave of the pandemic from new variants, such as the Variant of Concern-202012/01 from the B.1.1.7 lineage. Until today, many investigations in death cases of Coronavirus-disease-19 have been conducted, revealing pulmonary damage to be the predominant feature of the disease. Thereby, different degrees of macroscopic and microscopic lung damage have been reported, most of them resembling an Acute Respiratory Distress Syndrome. Far more, systemic complications of the disease such as pulmonary embolisms have been described. However, neither morphologic nor virologic findings of patients dying of the new variants have yet been reported. Here, we report on a comprehensive analysis of radiologic, morphologic, and virologic findings in a fatal case of this variant.
AB - The current pandemic with Severe acute respiratory syndrome-coronavirus-2 has been taking on new dynamics since the emergence of new variants last fall, some of them spreading more rapidly. Many countries currently find themselves in a race to ramp up vaccination strategies that have been initiated and a possible third wave of the pandemic from new variants, such as the Variant of Concern-202012/01 from the B.1.1.7 lineage. Until today, many investigations in death cases of Coronavirus-disease-19 have been conducted, revealing pulmonary damage to be the predominant feature of the disease. Thereby, different degrees of macroscopic and microscopic lung damage have been reported, most of them resembling an Acute Respiratory Distress Syndrome. Far more, systemic complications of the disease such as pulmonary embolisms have been described. However, neither morphologic nor virologic findings of patients dying of the new variants have yet been reported. Here, we report on a comprehensive analysis of radiologic, morphologic, and virologic findings in a fatal case of this variant.
U2 - 10.1007/s00414-021-02618-8
DO - 10.1007/s00414-021-02618-8
M3 - SCORING: Journal article
C2 - 34089348
VL - 136
SP - 193
EP - 202
JO - INT J LEGAL MED
JF - INT J LEGAL MED
SN - 0937-9827
IS - 1
ER -