DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study.

  • Götz Thomalla
  • Bastian Cheng
  • Martin Ebinger
  • Qing Hao
  • Thomas Tourdias
  • Ona Wu
  • Jong S Kim
  • Lorenz Breuer
  • Oliver C Singer
  • Steven Warach
  • Soren Christensen
  • András Treszl
  • Nils Forkert
  • Ivana Galinovic
  • Michael Rosenkranz
  • Tobias Engelhorn
  • Martin Köhrmann
  • Matthias Endres
  • Dong-Wha Kang
  • Vincent Dousset
  • A Gregory Sorensen
  • David S Liebeskind
  • Jochen B Fiebach
  • Jens Fiehler
  • Christian Gerloff
  • [Unbekannt] STIR
  • VISTA Imaging Investigators

Abstract

Many patients with stroke are precluded from thrombolysis treatment because the time from onset of their symptoms is unknown. We aimed to test whether a mismatch in visibility of an acute ischaemic lesion between diffusion-weighted MRI (DWI) and fluid-attenuated inversion recovery (FLAIR) MRI (DWI-FLAIR mismatch) can be used to detect patients within the recommended time window for thrombolysis.

Bibliographical data

Original languageEnglish
Article number11
ISSN1474-4422
Publication statusPublished - 2011
pubmed 21978972