Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest

Tiina Salminen; Caroline Garcia Forlim; Torsten Schubert; Simone Kühn

doi:10.1038/s41598-020-77310-9

Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest

Standard

Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest. / Salminen, Tiina; Forlim, Caroline Garcia; Schubert, Torsten; Kühn, Simone.

In: SCI REP-UK, Vol. 10, No. 1, 23.11.2020, p. 20379.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Salminen, T, Forlim, CG, Schubert, T & Kühn, S 2020, 'Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest', SCI REP-UK, vol. 10, no. 1, pp. 20379. https://doi.org/10.1038/s41598-020-77310-9

APA

Salminen, T., Forlim, C. G., Schubert, T., & Kühn, S. (2020). Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest. SCI REP-UK, 10(1), 20379. https://doi.org/10.1038/s41598-020-77310-9

Vancouver

Salminen T, Forlim CG, Schubert T, Kühn S. Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest. SCI REP-UK. 2020 Nov 23;10(1):20379. https://doi.org/10.1038/s41598-020-77310-9

Bibtex

@article{d15ebf4aef5343418b1fe6f43806cd14,

title = "Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest",

abstract = "Several studies have shown that the benefits of working memory (WM) training can be attributed to functional and structural neural changes in the underlying neural substrate. In the current study, we investigated whether the functional connectivity of the brain at rest in the default mode network (DMN) changes with WM training. We varied the complexity of the training intervention so, that half of the participants attended dual n-back training whereas the other half attended single n-back training. This way we could assess the effects of different training task parameters on possible connectivity changes. After 16 training sessions, the dual n-back training group showed improved performance accompanied by increased functional connectivity of the ventral DMN in the right inferior frontal gyrus, which correlated with improvements in WM. We also observed decreased functional connectivity in the left superior parietal cortex in this group. The single n-back training group did not show significant training-related changes. These results show that a demanding short-term WM training intervention can alter the default state of the brain.",

author = "Tiina Salminen and Forlim, {Caroline Garcia} and Torsten Schubert and Simone K{\"u}hn",

year = "2020",

month = nov,

day = "23",

doi = "10.1038/s41598-020-77310-9",

language = "English",

volume = "10",

pages = "20379",

journal = "SCI REP-UK",

issn = "2045-2322",

publisher = "NATURE PUBLISHING GROUP",

number = "1",

}

RIS

TY - JOUR

T1 - Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest

AU - Salminen, Tiina

AU - Forlim, Caroline Garcia

AU - Schubert, Torsten

AU - Kühn, Simone

PY - 2020/11/23

Y1 - 2020/11/23

N2 - Several studies have shown that the benefits of working memory (WM) training can be attributed to functional and structural neural changes in the underlying neural substrate. In the current study, we investigated whether the functional connectivity of the brain at rest in the default mode network (DMN) changes with WM training. We varied the complexity of the training intervention so, that half of the participants attended dual n-back training whereas the other half attended single n-back training. This way we could assess the effects of different training task parameters on possible connectivity changes. After 16 training sessions, the dual n-back training group showed improved performance accompanied by increased functional connectivity of the ventral DMN in the right inferior frontal gyrus, which correlated with improvements in WM. We also observed decreased functional connectivity in the left superior parietal cortex in this group. The single n-back training group did not show significant training-related changes. These results show that a demanding short-term WM training intervention can alter the default state of the brain.

AB - Several studies have shown that the benefits of working memory (WM) training can be attributed to functional and structural neural changes in the underlying neural substrate. In the current study, we investigated whether the functional connectivity of the brain at rest in the default mode network (DMN) changes with WM training. We varied the complexity of the training intervention so, that half of the participants attended dual n-back training whereas the other half attended single n-back training. This way we could assess the effects of different training task parameters on possible connectivity changes. After 16 training sessions, the dual n-back training group showed improved performance accompanied by increased functional connectivity of the ventral DMN in the right inferior frontal gyrus, which correlated with improvements in WM. We also observed decreased functional connectivity in the left superior parietal cortex in this group. The single n-back training group did not show significant training-related changes. These results show that a demanding short-term WM training intervention can alter the default state of the brain.

U2 - 10.1038/s41598-020-77310-9

DO - 10.1038/s41598-020-77310-9

M3 - SCORING: Journal article

C2 - 33230248

VL - 10

SP - 20379

JO - SCI REP-UK

JF - SCI REP-UK

SN - 2045-2322

IS - 1

ER -