Double-Blind, Randomized, Intraindividual Comparison Study of the Efficacy of Prilocaine and Lidocaine in Tumescent Local Anesthesia.
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Double-Blind, Randomized, Intraindividual Comparison Study of the Efficacy of Prilocaine and Lidocaine in Tumescent Local Anesthesia. / Augustin, Matthias; Maier, Kristina; Sommer, Boris; Sattler, Gerhard; Herberger, Katharina.
In: DERMATOLOGY, Vol. 221, No. 3, 3, 2010, p. 248-252.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Double-Blind, Randomized, Intraindividual Comparison Study of the Efficacy of Prilocaine and Lidocaine in Tumescent Local Anesthesia.
AU - Augustin, Matthias
AU - Maier, Kristina
AU - Sommer, Boris
AU - Sattler, Gerhard
AU - Herberger, Katharina
PY - 2010
Y1 - 2010
N2 - Background: Tumescent local anesthesia (TLA) with lidocaine or prilocaine solutions is widely used in dermatology. Objective: Comparison of efficacy and safety of lidocaine and prilocaine in liposuctions with TLA. Methods: TLA was performed using defined dilutions of lidocaine or prilocaine. Half-side comparisons were applied on 26 patients undergoing symmetric liposuction. Pain reduction (overall sensation and pain at lancet prick) and tolerance were assessed before, during and 2-24 h after liposuction. Results: No differences in overall pain sensation between the substances were detected during and after liposuction except a more rapid onset with lidocaine (less pain after 15 min, p <0.043). Local tolerance of both substances was excellent. Conclusion: Lidocaine and prilocaine used in TLA for liposuction show good efficacy and tolerance. A fixed combination of lidocaine and prilocaine may reduce the risk of side effects when great quantities of TLA are needed.
AB - Background: Tumescent local anesthesia (TLA) with lidocaine or prilocaine solutions is widely used in dermatology. Objective: Comparison of efficacy and safety of lidocaine and prilocaine in liposuctions with TLA. Methods: TLA was performed using defined dilutions of lidocaine or prilocaine. Half-side comparisons were applied on 26 patients undergoing symmetric liposuction. Pain reduction (overall sensation and pain at lancet prick) and tolerance were assessed before, during and 2-24 h after liposuction. Results: No differences in overall pain sensation between the substances were detected during and after liposuction except a more rapid onset with lidocaine (less pain after 15 min, p <0.043). Local tolerance of both substances was excellent. Conclusion: Lidocaine and prilocaine used in TLA for liposuction show good efficacy and tolerance. A fixed combination of lidocaine and prilocaine may reduce the risk of side effects when great quantities of TLA are needed.
M3 - SCORING: Zeitschriftenaufsatz
VL - 221
SP - 248
EP - 252
JO - DERMATOLOGY
JF - DERMATOLOGY
SN - 1018-8665
IS - 3
M1 - 3
ER -
