Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.

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Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia. / Hessling, Jörg; Kröger, Nicolaus-Martin; Werner, Mathias; Zabelina, Tatjana; Hansen, Arne; Kordes, Uwe; Ayuketang Ayuk, Francis; Renges, Helmut-Hans; Panse, Jens; Erttmann, Rudolf; Zander, Axel.

In: BRIT J HAEMATOL, Vol. 119, No. 3, 3, 2002, p. 769-772.

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@article{b1f437425e144fb98bd41744c5b818fa,
title = "Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.",
abstract = "Three patients with myelofibrosis received allogeneic stem cell transplantation after a dose-reduced conditioning regimen of busulphan (8 mg/kg), fludarabine (180 mg/m2) and antithymocyte globulin (4 x 10 mg/kg). The median age at transplantation was 51 years (range 44-58). All patients engrafted with a leucocyte count > 1.0 x 10(9)/l after a median of 18 d (range 16-20). Grade II acute skin graft-versus-host disease (GvHD) occurred in one patient. One limited and one extensive chronic GvHD was observed. All patients achieved complete haematological remission. In one patient the fibrosis resolved completely 180 d post transplant. All patients are alive 126, 466 and 764 d after transplantation.",
author = "J{\"o}rg Hessling and Nicolaus-Martin Kr{\"o}ger and Mathias Werner and Tatjana Zabelina and Arne Hansen and Uwe Kordes and {Ayuketang Ayuk}, Francis and Helmut-Hans Renges and Jens Panse and Rudolf Erttmann and Axel Zander",
year = "2002",
language = "Deutsch",
volume = "119",
pages = "769--772",
journal = "BRIT J HAEMATOL",
issn = "0007-1048",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.

AU - Hessling, Jörg

AU - Kröger, Nicolaus-Martin

AU - Werner, Mathias

AU - Zabelina, Tatjana

AU - Hansen, Arne

AU - Kordes, Uwe

AU - Ayuketang Ayuk, Francis

AU - Renges, Helmut-Hans

AU - Panse, Jens

AU - Erttmann, Rudolf

AU - Zander, Axel

PY - 2002

Y1 - 2002

N2 - Three patients with myelofibrosis received allogeneic stem cell transplantation after a dose-reduced conditioning regimen of busulphan (8 mg/kg), fludarabine (180 mg/m2) and antithymocyte globulin (4 x 10 mg/kg). The median age at transplantation was 51 years (range 44-58). All patients engrafted with a leucocyte count > 1.0 x 10(9)/l after a median of 18 d (range 16-20). Grade II acute skin graft-versus-host disease (GvHD) occurred in one patient. One limited and one extensive chronic GvHD was observed. All patients achieved complete haematological remission. In one patient the fibrosis resolved completely 180 d post transplant. All patients are alive 126, 466 and 764 d after transplantation.

AB - Three patients with myelofibrosis received allogeneic stem cell transplantation after a dose-reduced conditioning regimen of busulphan (8 mg/kg), fludarabine (180 mg/m2) and antithymocyte globulin (4 x 10 mg/kg). The median age at transplantation was 51 years (range 44-58). All patients engrafted with a leucocyte count > 1.0 x 10(9)/l after a median of 18 d (range 16-20). Grade II acute skin graft-versus-host disease (GvHD) occurred in one patient. One limited and one extensive chronic GvHD was observed. All patients achieved complete haematological remission. In one patient the fibrosis resolved completely 180 d post transplant. All patients are alive 126, 466 and 764 d after transplantation.

M3 - SCORING: Zeitschriftenaufsatz

VL - 119

SP - 769

EP - 772

JO - BRIT J HAEMATOL

JF - BRIT J HAEMATOL

SN - 0007-1048

IS - 3

M1 - 3

ER -