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Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus

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Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus. / Petersen, Rasmus S; Brambilla, Marco; Bale, Michael R; Alenda, Andrea; UK, Faculty of Life Sciences University of Manchester Manchester M60; Montemurro, Marcelo A; Maravall, Miguel.

In: NEURON, Vol. 60, No. 5, 10.12.2008, p. 890-903.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Petersen, RS, Brambilla, M, Bale, MR, Alenda, A, UK, FOLSUOMMM, Montemurro, MA & Maravall, M 2008, 'Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus', NEURON, vol. 60, no. 5, pp. 890-903. https://doi.org/10.1016/j.neuron.2008.09.041

APA

Petersen, R. S., Brambilla, M., Bale, M. R., Alenda, A., UK, F. O. L. S. U. O. M. M. M., Montemurro, M. A., & Maravall, M. (2008). Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus. NEURON, 60(5), 890-903. https://doi.org/10.1016/j.neuron.2008.09.041

Vancouver

Petersen RS, Brambilla M, Bale MR, Alenda A, UK FOLSUOMMM, Montemurro MA et al. Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus. NEURON. 2008 Dec 10;60(5):890-903. https://doi.org/10.1016/j.neuron.2008.09.041

Bibtex

@article{27643df62c054f7d8f7f935d6aab8964,
title = "Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus",
abstract = "The thalamo-cortical pathway is the crucial sensory gateway into the cerebral cortex. We aimed to determine the nature of the tactile information encoded by neurons in the whisker somatosensory relay nucleus (VPm). We wanted to distinguish whether VPm neurons encode similar stimulus features, acting as a single information channel, or encode diverse features. We recorded responses to whisker deflections that thoroughly explored the space of temporal stimulus variables and identified features to which neurons were selective by reverse correlation. The timescale of the features was typically 1-2 ms, at the limit imposed by our experimental conditions, indicating highly acute feature selectivity. Sensitivity to stimulus kinetics was strikingly diverse. Some neurons (25%) only encoded velocity; others were sensitive to position, acceleration, or more complex features. A minority (19%) encoded two or more features. These results indicate that VPm contains a distributed representation of whisker motion, based on high-resolution kinetic features.",
keywords = "Action Potentials/physiology, Animals, Biomechanical Phenomena, Brain Mapping, Models, Biological, Neurons, Afferent/classification, Physical Stimulation/methods, Rats, Rats, Wistar, Time Factors, Ventral Thalamic Nuclei/cytology, Vibrissae/innervation",
author = "Petersen, {Rasmus S} and Marco Brambilla and Bale, {Michael R} and Andrea Alenda and UK, {Faculty of Life Sciences University of Manchester Manchester M60} and Montemurro, {Marcelo A} and Miguel Maravall",
year = "2008",
month = dec,
day = "10",
doi = "10.1016/j.neuron.2008.09.041",
language = "English",
volume = "60",
pages = "890--903",
journal = "NEURON",
issn = "0896-6273",
publisher = "Cell Press",
number = "5",

}

RIS

TY - JOUR

T1 - Diverse and temporally precise kinetic feature selectivity in the VPm thalamic nucleus

AU - Petersen, Rasmus S

AU - Brambilla, Marco

AU - Bale, Michael R

AU - Alenda, Andrea

AU - UK, Faculty of Life Sciences University of Manchester Manchester M60

AU - Montemurro, Marcelo A

AU - Maravall, Miguel

PY - 2008/12/10

Y1 - 2008/12/10

N2 - The thalamo-cortical pathway is the crucial sensory gateway into the cerebral cortex. We aimed to determine the nature of the tactile information encoded by neurons in the whisker somatosensory relay nucleus (VPm). We wanted to distinguish whether VPm neurons encode similar stimulus features, acting as a single information channel, or encode diverse features. We recorded responses to whisker deflections that thoroughly explored the space of temporal stimulus variables and identified features to which neurons were selective by reverse correlation. The timescale of the features was typically 1-2 ms, at the limit imposed by our experimental conditions, indicating highly acute feature selectivity. Sensitivity to stimulus kinetics was strikingly diverse. Some neurons (25%) only encoded velocity; others were sensitive to position, acceleration, or more complex features. A minority (19%) encoded two or more features. These results indicate that VPm contains a distributed representation of whisker motion, based on high-resolution kinetic features.

AB - The thalamo-cortical pathway is the crucial sensory gateway into the cerebral cortex. We aimed to determine the nature of the tactile information encoded by neurons in the whisker somatosensory relay nucleus (VPm). We wanted to distinguish whether VPm neurons encode similar stimulus features, acting as a single information channel, or encode diverse features. We recorded responses to whisker deflections that thoroughly explored the space of temporal stimulus variables and identified features to which neurons were selective by reverse correlation. The timescale of the features was typically 1-2 ms, at the limit imposed by our experimental conditions, indicating highly acute feature selectivity. Sensitivity to stimulus kinetics was strikingly diverse. Some neurons (25%) only encoded velocity; others were sensitive to position, acceleration, or more complex features. A minority (19%) encoded two or more features. These results indicate that VPm contains a distributed representation of whisker motion, based on high-resolution kinetic features.

KW - Action Potentials/physiology

KW - Animals

KW - Biomechanical Phenomena

KW - Brain Mapping

KW - Models, Biological

KW - Neurons, Afferent/classification

KW - Physical Stimulation/methods

KW - Rats

KW - Rats, Wistar

KW - Time Factors

KW - Ventral Thalamic Nuclei/cytology

KW - Vibrissae/innervation

U2 - 10.1016/j.neuron.2008.09.041

DO - 10.1016/j.neuron.2008.09.041

M3 - SCORING: Journal article

C2 - 19081382

VL - 60

SP - 890

EP - 903

JO - NEURON

JF - NEURON

SN - 0896-6273

IS - 5

ER -