Distributed neural system for general intelligence revealed by lesion mapping.
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Distributed neural system for general intelligence revealed by lesion mapping. / Gläscher, Jan; Rudrauf, D; Colom, R; Paul, L K; Tranel, D; Damasio, H; Adolphs, R.
In: P NATL ACAD SCI USA, Vol. 107, No. 10, 10, 2010, p. 4705-4709.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Distributed neural system for general intelligence revealed by lesion mapping.
AU - Gläscher, Jan
AU - Rudrauf, D
AU - Colom, R
AU - Paul, L K
AU - Tranel, D
AU - Damasio, H
AU - Adolphs, R
PY - 2010
Y1 - 2010
N2 - General intelligence (g) captures the performance variance shared across cognitive tasks and correlates with real-world success. Yet it remains debated whether g reflects the combined performance of brain systems involved in these tasks or draws on specialized systems mediating their interactions. Here we investigated the neural substrates of g in 241 patients with focal brain damage using voxel-based lesion-symptom mapping. A hierarchical factor analysis across multiple cognitive tasks was used to derive a robust measure of g. Statistically significant associations were found between g and damage to a remarkably circumscribed albeit distributed network in frontal and parietal cortex, critically including white matter association tracts and frontopolar cortex. We suggest that general intelligence draws on connections between regions that integrate verbal, visuospatial, working memory, and executive processes.
AB - General intelligence (g) captures the performance variance shared across cognitive tasks and correlates with real-world success. Yet it remains debated whether g reflects the combined performance of brain systems involved in these tasks or draws on specialized systems mediating their interactions. Here we investigated the neural substrates of g in 241 patients with focal brain damage using voxel-based lesion-symptom mapping. A hierarchical factor analysis across multiple cognitive tasks was used to derive a robust measure of g. Statistically significant associations were found between g and damage to a remarkably circumscribed albeit distributed network in frontal and parietal cortex, critically including white matter association tracts and frontopolar cortex. We suggest that general intelligence draws on connections between regions that integrate verbal, visuospatial, working memory, and executive processes.
M3 - SCORING: Zeitschriftenaufsatz
VL - 107
SP - 4705
EP - 4709
JO - P NATL ACAD SCI USA
JF - P NATL ACAD SCI USA
SN - 0027-8424
IS - 10
M1 - 10
ER -
