Differential expression of the estrogen receptor-related receptor gamma in the mouse brain
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Differential expression of the estrogen receptor-related receptor gamma in the mouse brain. / Lorke, D E; Süsens, U; Borgmeyer, U; Hermans-Borgmeyer, I.
In: MOL BRAIN RES, Vol. 77, No. 2, 05.05.2000, p. 277-80.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Differential expression of the estrogen receptor-related receptor gamma in the mouse brain
AU - Lorke, D E
AU - Süsens, U
AU - Borgmeyer, U
AU - Hermans-Borgmeyer, I
PY - 2000/5/5
Y1 - 2000/5/5
N2 - To elucidate estrogen functions, the expression of the estrogen receptor-related receptor ERRgamma, a novel orphan nuclear receptor regulating transcription via estrogen responsive elements, has been localized by in situ hybridization in adult murine brain. ERRgamma transcripts were abundantly present in the isocortex, the olfactory system, cranial nerve nuclei and major parts of the coordination centers, e.g. reticular formation and major parts of the extrapyramidal motor systems. In addition, ERRgamma expression was detected in trigeminal ganglion neurons. ERRgamma distribution was clearly distinguished from that described for ERRalpha, for ERRbeta, and for estrogen receptors (ER) pointing at functional differences between ERRgamma and these receptors.
AB - To elucidate estrogen functions, the expression of the estrogen receptor-related receptor ERRgamma, a novel orphan nuclear receptor regulating transcription via estrogen responsive elements, has been localized by in situ hybridization in adult murine brain. ERRgamma transcripts were abundantly present in the isocortex, the olfactory system, cranial nerve nuclei and major parts of the coordination centers, e.g. reticular formation and major parts of the extrapyramidal motor systems. In addition, ERRgamma expression was detected in trigeminal ganglion neurons. ERRgamma distribution was clearly distinguished from that described for ERRalpha, for ERRbeta, and for estrogen receptors (ER) pointing at functional differences between ERRgamma and these receptors.
KW - Animals
KW - Brain
KW - Gene Expression
KW - In Situ Hybridization
KW - Mice
KW - RNA, Messenger
KW - Receptors, Cytoplasmic and Nuclear
KW - Receptors, Estrogen
M3 - SCORING: Journal article
C2 - 10837923
VL - 77
SP - 277
EP - 280
IS - 2
ER -