Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone.

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Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone. / Demiralay, Cüneyt; Jahn, Holger; Kellner, Michael; Yassouridis, Alexander; Wiedemann, Klaus.

In: WORLD J BIOL PSYCHIA, Vol. 13, No. 7, 7, 2012, p. 526-534.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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Demiralay C, Jahn H, Kellner M, Yassouridis A, Wiedemann K. Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone. WORLD J BIOL PSYCHIA. 2012;13(7):526-534. 7.

Bibtex

@article{cf92abbc2c2d416eae7c0260274a2285,
title = "Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone.",
abstract = "Peripheral administration of the cholecystokinin (CCK) receptor agonist CCK-4 generates panic and activates the hypothalamic-pituitary-adrenal (HPA) axis. Direct effects at the pituitary and CCK-HPA interactions at higher regulatory sites have been suggested. According to preliminary data, ACTH response to CCK receptor agonists may differ from its response to exogenous CRH by its resistance to cortisol feedback inhibition. To further explore this resistance and to better characterize CCK-4 sites of action, the effects of different glucocorticoid pretreatments on CCK-4-induced panic were compared.",
keywords = "Adult, Humans, Male, Severity of Illness Index, Double-Blind Method, Analysis of Variance, Anti-Inflammatory Agents/*pharmacology, Adrenocorticotropic Hormone/blood, Psychiatric Status Rating Scales/statistics & numerical data, Panic Disorder/*chemically induced/*drug therapy, Dexamethasone/*pharmacology, Hydrocortisone/blood/*pharmacology, Tetragastrin/*pharmacology, Adult, Humans, Male, Severity of Illness Index, Double-Blind Method, Analysis of Variance, Anti-Inflammatory Agents/*pharmacology, Adrenocorticotropic Hormone/blood, Psychiatric Status Rating Scales/statistics & numerical data, Panic Disorder/*chemically induced/*drug therapy, Dexamethasone/*pharmacology, Hydrocortisone/blood/*pharmacology, Tetragastrin/*pharmacology",
author = "C{\"u}neyt Demiralay and Holger Jahn and Michael Kellner and Alexander Yassouridis and Klaus Wiedemann",
year = "2012",
language = "English",
volume = "13",
pages = "526--534",
journal = "WORLD J BIOL PSYCHIA",
issn = "1562-2975",
publisher = "informa healthcare",
number = "7",

}

RIS

TY - JOUR

T1 - Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone.

AU - Demiralay, Cüneyt

AU - Jahn, Holger

AU - Kellner, Michael

AU - Yassouridis, Alexander

AU - Wiedemann, Klaus

PY - 2012

Y1 - 2012

N2 - Peripheral administration of the cholecystokinin (CCK) receptor agonist CCK-4 generates panic and activates the hypothalamic-pituitary-adrenal (HPA) axis. Direct effects at the pituitary and CCK-HPA interactions at higher regulatory sites have been suggested. According to preliminary data, ACTH response to CCK receptor agonists may differ from its response to exogenous CRH by its resistance to cortisol feedback inhibition. To further explore this resistance and to better characterize CCK-4 sites of action, the effects of different glucocorticoid pretreatments on CCK-4-induced panic were compared.

AB - Peripheral administration of the cholecystokinin (CCK) receptor agonist CCK-4 generates panic and activates the hypothalamic-pituitary-adrenal (HPA) axis. Direct effects at the pituitary and CCK-HPA interactions at higher regulatory sites have been suggested. According to preliminary data, ACTH response to CCK receptor agonists may differ from its response to exogenous CRH by its resistance to cortisol feedback inhibition. To further explore this resistance and to better characterize CCK-4 sites of action, the effects of different glucocorticoid pretreatments on CCK-4-induced panic were compared.

KW - Adult

KW - Humans

KW - Male

KW - Severity of Illness Index

KW - Double-Blind Method

KW - Analysis of Variance

KW - Anti-Inflammatory Agents/pharmacology

KW - Adrenocorticotropic Hormone/blood

KW - Psychiatric Status Rating Scales/statistics & numerical data

KW - Panic Disorder/chemically induced/drug therapy

KW - Dexamethasone/pharmacology

KW - Hydrocortisone/blood/pharmacology

KW - Tetragastrin/pharmacology

KW - Adult

KW - Humans

KW - Male

KW - Severity of Illness Index

KW - Double-Blind Method

KW - Analysis of Variance

KW - Anti-Inflammatory Agents/pharmacology

KW - Adrenocorticotropic Hormone/blood

KW - Psychiatric Status Rating Scales/statistics & numerical data

KW - Panic Disorder/chemically induced/drug therapy

KW - Dexamethasone/pharmacology

KW - Hydrocortisone/blood/pharmacology

KW - Tetragastrin/pharmacology

M3 - SCORING: Journal article

VL - 13

SP - 526

EP - 534

JO - WORLD J BIOL PSYCHIA

JF - WORLD J BIOL PSYCHIA

SN - 1562-2975

IS - 7

M1 - 7

ER -