Research ExplorerPublicationsDifferences in overall survival between clear cell metastati...

Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States

Standard

Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States. / Cano Garcia, Cristina; Nimer, Nancy; Piccinelli, Mattia Luca; Tappero, Stefano; Panunzio, Andrea; Barletta, Francesco; Incesu, Reha-Baris; Tian, Zhe; Saad, Fred; Kapoor, Anil; Briganti, Alberto; Terrone, Carlo; Shariat, Shahrokh F; Tilki, Derya; Antonelli, Alessandro; De Cobelli, Ottavio; Kluth, Luis A; Becker, Andreas; Chun, Felix K H; Karakiewicz, Pierre I.

In: ANN EPIDEMIOL, Vol. 79, 03.2023, p. 65-70.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Cano Garcia, C, Nimer, N, Piccinelli, ML, Tappero, S, Panunzio, A, Barletta, F, Incesu, R-B, Tian, Z, Saad, F, Kapoor, A, Briganti, A, Terrone, C, Shariat, SF, Tilki, D, Antonelli, A, De Cobelli, O, Kluth, LA, Becker, A, Chun, FKH & Karakiewicz, PI 2023, 'Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States', ANN EPIDEMIOL, vol. 79, pp. 65-70. https://doi.org/10.1016/j.annepidem.2023.01.003

APA

Cano Garcia, C., Nimer, N., Piccinelli, M. L., Tappero, S., Panunzio, A., Barletta, F., Incesu, R-B., Tian, Z., Saad, F., Kapoor, A., Briganti, A., Terrone, C., Shariat, S. F., Tilki, D., Antonelli, A., De Cobelli, O., Kluth, L. A., Becker, A., Chun, F. K. H., & Karakiewicz, P. I. (2023). Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States. ANN EPIDEMIOL, 79, 65-70. https://doi.org/10.1016/j.annepidem.2023.01.003

Vancouver

Cano Garcia C, Nimer N, Piccinelli ML, Tappero S, Panunzio A, Barletta F et al. Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States. ANN EPIDEMIOL. 2023 Mar;79:65-70. https://doi.org/10.1016/j.annepidem.2023.01.003

Bibtex

@article{e07abfb88be2452ab5948611bd6cc65e,
title = "Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States",
abstract = "PURPOSE: To quantify differences in five-year overall survival (OS) between clear cell metastatic renal cell carcinoma (ccmRCC) patients and age- and sex-matched population-based controls, especially when race/ethnicity is considered.METHODS: We relied on the Surveillance, Epidemiology and End Results database (2006-2016) to identify newly diagnosed (2006- 2011) ccmRCC patients of either Caucasian, Hispanic, African American, or Asian/Pacific Islander race/ethnicity. For each case, we simulated an age- and sex-matched control (Monte Carlo simulation), relying on Social Security Administration Life Tables with five-year follow-up. We compared OS between ccmRCC patients and controls. Multivariable Cox regression models tested for race/ethnicity effect on OS.RESULTS: Of 3067 ccmRCC patients, 2167 (71%) were Caucasians vs. 488 (16%) Hispanics vs. 216 (7%) African Americans and 196 (6%) Asians/Pacific Islanders. At five years, OS difference between ccmRCC patients vs. population-based controls was greatest in African Americans (11 vs. 94%, Δ = 84%), followed by Hispanics (16 vs. 94%, Δ = 77%), Caucasians (16 vs. 89%, Δ = 73%) and Asians/Pacific Islanders (19 vs. 88%, Δ = 70%). In multivariable Cox regression models, African Americans exhibited highest Hazard Ratio for death (HR 1.3, p= 0.003).CONCLUSION: Relative to Life Tables' derived age- and sex-matched controls, ccmRCC patients exhibit drastically worse OS, especially African Americans.",
keywords = "Humans, United States/epidemiology, Carcinoma, Renal Cell, Ethnicity, Kidney Neoplasms/pathology, SEER Program",
author = "{Cano Garcia}, Cristina and Nancy Nimer and Piccinelli, {Mattia Luca} and Stefano Tappero and Andrea Panunzio and Francesco Barletta and Reha-Baris Incesu and Zhe Tian and Fred Saad and Anil Kapoor and Alberto Briganti and Carlo Terrone and Shariat, {Shahrokh F} and Derya Tilki and Alessandro Antonelli and {De Cobelli}, Ottavio and Kluth, {Luis A} and Andreas Becker and Chun, {Felix K H} and Karakiewicz, {Pierre I}",
note = "Copyright {\textcopyright} 2023 Elsevier Inc. All rights reserved.",
year = "2023",
month = mar,
doi = "10.1016/j.annepidem.2023.01.003",
language = "English",
volume = "79",
pages = "65--70",
journal = "ANN EPIDEMIOL",
issn = "1047-2797",
publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States

AU - Cano Garcia, Cristina

AU - Nimer, Nancy

AU - Piccinelli, Mattia Luca

AU - Tappero, Stefano

AU - Panunzio, Andrea

AU - Barletta, Francesco

AU - Incesu, Reha-Baris

AU - Tian, Zhe

AU - Saad, Fred

AU - Kapoor, Anil

AU - Briganti, Alberto

AU - Terrone, Carlo

AU - Shariat, Shahrokh F

AU - Tilki, Derya

AU - Antonelli, Alessandro

AU - De Cobelli, Ottavio

AU - Kluth, Luis A

AU - Becker, Andreas

AU - Chun, Felix K H

AU - Karakiewicz, Pierre I

N1 - Copyright © 2023 Elsevier Inc. All rights reserved.

PY - 2023/3

Y1 - 2023/3

N2 - PURPOSE: To quantify differences in five-year overall survival (OS) between clear cell metastatic renal cell carcinoma (ccmRCC) patients and age- and sex-matched population-based controls, especially when race/ethnicity is considered.METHODS: We relied on the Surveillance, Epidemiology and End Results database (2006-2016) to identify newly diagnosed (2006- 2011) ccmRCC patients of either Caucasian, Hispanic, African American, or Asian/Pacific Islander race/ethnicity. For each case, we simulated an age- and sex-matched control (Monte Carlo simulation), relying on Social Security Administration Life Tables with five-year follow-up. We compared OS between ccmRCC patients and controls. Multivariable Cox regression models tested for race/ethnicity effect on OS.RESULTS: Of 3067 ccmRCC patients, 2167 (71%) were Caucasians vs. 488 (16%) Hispanics vs. 216 (7%) African Americans and 196 (6%) Asians/Pacific Islanders. At five years, OS difference between ccmRCC patients vs. population-based controls was greatest in African Americans (11 vs. 94%, Δ = 84%), followed by Hispanics (16 vs. 94%, Δ = 77%), Caucasians (16 vs. 89%, Δ = 73%) and Asians/Pacific Islanders (19 vs. 88%, Δ = 70%). In multivariable Cox regression models, African Americans exhibited highest Hazard Ratio for death (HR 1.3, p= 0.003).CONCLUSION: Relative to Life Tables' derived age- and sex-matched controls, ccmRCC patients exhibit drastically worse OS, especially African Americans.

AB - PURPOSE: To quantify differences in five-year overall survival (OS) between clear cell metastatic renal cell carcinoma (ccmRCC) patients and age- and sex-matched population-based controls, especially when race/ethnicity is considered.METHODS: We relied on the Surveillance, Epidemiology and End Results database (2006-2016) to identify newly diagnosed (2006- 2011) ccmRCC patients of either Caucasian, Hispanic, African American, or Asian/Pacific Islander race/ethnicity. For each case, we simulated an age- and sex-matched control (Monte Carlo simulation), relying on Social Security Administration Life Tables with five-year follow-up. We compared OS between ccmRCC patients and controls. Multivariable Cox regression models tested for race/ethnicity effect on OS.RESULTS: Of 3067 ccmRCC patients, 2167 (71%) were Caucasians vs. 488 (16%) Hispanics vs. 216 (7%) African Americans and 196 (6%) Asians/Pacific Islanders. At five years, OS difference between ccmRCC patients vs. population-based controls was greatest in African Americans (11 vs. 94%, Δ = 84%), followed by Hispanics (16 vs. 94%, Δ = 77%), Caucasians (16 vs. 89%, Δ = 73%) and Asians/Pacific Islanders (19 vs. 88%, Δ = 70%). In multivariable Cox regression models, African Americans exhibited highest Hazard Ratio for death (HR 1.3, p= 0.003).CONCLUSION: Relative to Life Tables' derived age- and sex-matched controls, ccmRCC patients exhibit drastically worse OS, especially African Americans.

KW - Humans

KW - United States/epidemiology

KW - Carcinoma, Renal Cell

KW - Ethnicity

KW - Kidney Neoplasms/pathology

KW - SEER Program

U2 - 10.1016/j.annepidem.2023.01.003

DO - 10.1016/j.annepidem.2023.01.003

M3 - SCORING: Journal article

C2 - 36640918

VL - 79

SP - 65

EP - 70

JO - ANN EPIDEMIOL

JF - ANN EPIDEMIOL

SN - 1047-2797

ER -