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Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

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Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis. / Molina, Cristina E; Heijman, Jordi; Dobrev, Dobromir.

In: ARRHYTH ELECTROPHYSI, Vol. 5, No. 1, 05.2016, p. 14-9.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Molina, CE, Heijman, J & Dobrev, D 2016, 'Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis', ARRHYTH ELECTROPHYSI, vol. 5, no. 1, pp. 14-9. https://doi.org/10.15420/aer.2016.8.2

APA

Molina, C. E., Heijman, J., & Dobrev, D. (2016). Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis. ARRHYTH ELECTROPHYSI, 5(1), 14-9. https://doi.org/10.15420/aer.2016.8.2

Vancouver

Molina CE, Heijman J, Dobrev D. Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis. ARRHYTH ELECTROPHYSI. 2016 May;5(1):14-9. https://doi.org/10.15420/aer.2016.8.2

Bibtex

@article{4ac910ff46984eefbe3c85b92bf60ad3,
title = "Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis",
abstract = "A wide range of ion channels, transporters, signaling pathways and tissue structure at a microscopic and macroscopic scale regulate the electrophysiological activity of the heart. Each region of the heart has optimised these properties based on its specific role during the cardiac cycle, leading to well-established differences in electrophysiology, Ca(2+) handling and tissue structure between atria and ventricles and between different layers of the ventricular wall. Similarly, the right ventricle (RV) and left ventricle (LV) have different embryological, structural, metabolic and electrophysiological features, but whether interventricular differences promote differential remodeling leading to arrhythmias is not well understood. In this article, we will summarise the available data on intrinsic differences between LV and RV electrophysiology and indicate how these differences affect cardiac function. Furthermore, we will discuss the differential remodeling of both chambers in pathological conditions and its potential impact on arrhythmogenesis. ",
keywords = "Journal Article",
author = "Molina, {Cristina E} and Jordi Heijman and Dobromir Dobrev",
year = "2016",
month = may,
doi = "10.15420/aer.2016.8.2",
language = "English",
volume = "5",
pages = "14--9",
journal = "ARRHYTH ELECTROPHYSI",
issn = "2050-3369",
publisher = "Science Publishing Corporation Inc",
number = "1",

}

RIS

TY - JOUR

T1 - Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

AU - Molina, Cristina E

AU - Heijman, Jordi

AU - Dobrev, Dobromir

PY - 2016/5

Y1 - 2016/5

N2 - A wide range of ion channels, transporters, signaling pathways and tissue structure at a microscopic and macroscopic scale regulate the electrophysiological activity of the heart. Each region of the heart has optimised these properties based on its specific role during the cardiac cycle, leading to well-established differences in electrophysiology, Ca(2+) handling and tissue structure between atria and ventricles and between different layers of the ventricular wall. Similarly, the right ventricle (RV) and left ventricle (LV) have different embryological, structural, metabolic and electrophysiological features, but whether interventricular differences promote differential remodeling leading to arrhythmias is not well understood. In this article, we will summarise the available data on intrinsic differences between LV and RV electrophysiology and indicate how these differences affect cardiac function. Furthermore, we will discuss the differential remodeling of both chambers in pathological conditions and its potential impact on arrhythmogenesis.

AB - A wide range of ion channels, transporters, signaling pathways and tissue structure at a microscopic and macroscopic scale regulate the electrophysiological activity of the heart. Each region of the heart has optimised these properties based on its specific role during the cardiac cycle, leading to well-established differences in electrophysiology, Ca(2+) handling and tissue structure between atria and ventricles and between different layers of the ventricular wall. Similarly, the right ventricle (RV) and left ventricle (LV) have different embryological, structural, metabolic and electrophysiological features, but whether interventricular differences promote differential remodeling leading to arrhythmias is not well understood. In this article, we will summarise the available data on intrinsic differences between LV and RV electrophysiology and indicate how these differences affect cardiac function. Furthermore, we will discuss the differential remodeling of both chambers in pathological conditions and its potential impact on arrhythmogenesis.

KW - Journal Article

U2 - 10.15420/aer.2016.8.2

DO - 10.15420/aer.2016.8.2

M3 - SCORING: Journal article

C2 - 27403288

VL - 5

SP - 14

EP - 19

JO - ARRHYTH ELECTROPHYSI

JF - ARRHYTH ELECTROPHYSI

SN - 2050-3369

IS - 1

ER -