Diagnosis of Parkinson's disease--transcranial sonography in relation to MRI.
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Diagnosis of Parkinson's disease--transcranial sonography in relation to MRI. / Niehaus, Ludwig; Boelmans, Kai.
In: INT REV NEUROBIOL, Vol. 90, 2010, p. 63-79.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Diagnosis of Parkinson's disease--transcranial sonography in relation to MRI.
AU - Niehaus, Ludwig
AU - Boelmans, Kai
PY - 2010
Y1 - 2010
N2 - Displaying the echo pattern (echogenicity) of brain tissue transcranial sonography (TCS) may provide new and complementary information to other neuroimaging methods. In contrast to conventional magnetic resonance imaging (MRI), TCS is able to detect highly characteristic changes in signal brightness of the substantia nigra (SN) in patients with idiopathic Parkinson's disease. In this review, TCS findings are related to conventional and advanced high-field brain MRI findings. On the basis of the MRI findings, especially with T2-relaxometry, the possible role of trace metals in the genesis of altered echogenicity on TCS of brain parenchyma, especially of the SN, are discussed.
AB - Displaying the echo pattern (echogenicity) of brain tissue transcranial sonography (TCS) may provide new and complementary information to other neuroimaging methods. In contrast to conventional magnetic resonance imaging (MRI), TCS is able to detect highly characteristic changes in signal brightness of the substantia nigra (SN) in patients with idiopathic Parkinson's disease. In this review, TCS findings are related to conventional and advanced high-field brain MRI findings. On the basis of the MRI findings, especially with T2-relaxometry, the possible role of trace metals in the genesis of altered echogenicity on TCS of brain parenchyma, especially of the SN, are discussed.
M3 - SCORING: Zeitschriftenaufsatz
VL - 90
SP - 63
EP - 79
JO - INT REV NEUROBIOL
JF - INT REV NEUROBIOL
SN - 0074-7742
ER -
