Development and first results of a national databank on care and treatment outcome after traumatic brain injury

TY - JOUR

T1 - Development and first results of a national databank on care and treatment outcome after traumatic brain injury

AU - Younsi, Alexander

AU - Unterberg, Andreas

AU - Marzi, Ingo

AU - Steudel, Wolf-Ingo

AU - Uhl, Eberhard

AU - Lemcke, Johannes

AU - Berg, Florian

AU - Woschek, Mathias

AU - Friedrich, Michaela

AU - Clusmann, Hans

AU - Hamou, Hussam Aldin

AU - Mauer, Uwe Max

AU - Scheer, Magnus

AU - Meixensberger, Jürgen

AU - Lindner, Dirk

AU - Schmieder, Kirsten

AU - Gierthmuehlen, Mortimer

AU - Hoefer, Christine

AU - Nienaber, Ulrike

AU - Maegele, Marc

AU - TBI Databank Expert Group

AU - Czorlich, Patrick

AU - Emami, Pedram

N1 - © 2023. The Author(s).

PY - 2023/6

Y1 - 2023/6

N2 - PURPOSE: In absence of comprehensive data collection on traumatic brain injury (TBI), the German Society for Neurosurgery (DGNC) and the German Society for Trauma Surgery (DGU) developed a TBI databank for German-speaking countries.METHODS: From 2016 to 2020, the TBI databank DGNC/DGU was implemented as a module of the TraumaRegister (TR) DGU and tested in a 15-month pilot phase. Since its official launch in 2021, patients from the TR-DGU (intermediate or intensive care unit admission via shock room) with TBI (AIS head ≥ 1) can be enrolled. A data set of > 300 clinical, imaging, and laboratory variables, harmonized with other international TBI data collection structures is documented, and the treatment outcome is evaluated after 6- and 12 months.RESULTS: For this analysis, 318 patients in the TBI databank could be included (median age 58 years; 71% men). Falls were the most common cause of injury (55%), and antithrombotic medication was frequent (28%). Severe or moderate TBI were only present in 55% of patients, while 45% suffered a mild injury. Nevertheless, intracranial pathologies were present in 95% of brain imaging with traumatic subarachnoid hemorrhages (76%) being the most common. Intracranial surgeries were performed in 42% of cases. In-hospital mortality after TBI was 21% and surviving patients could be discharged after a median hospital stay of 11 days. At the 6-and 12 months follow-up, a favorable outcome was achieved by 70% and 90% of the participating TBI patients, respectively. Compared to a European cohort of 2138 TBI patients treated in the ICU between 2014 and 2017, patients in the TBI databank were already older, frailer, fell more commonly at home.CONCLUSION: Within five years, the TBI databank DGNC/DGU of the TR-DGU could be established and is since then prospectively enrolling TBI patients in German-speaking countries. With its large and harmonized data set and a 12-month follow-up, the TBI databank is a unique project in Europe, already allowing comparisons to other data collection structures and indicating a demographic change towards older and frailer TBI patients in Germany.

AB - PURPOSE: In absence of comprehensive data collection on traumatic brain injury (TBI), the German Society for Neurosurgery (DGNC) and the German Society for Trauma Surgery (DGU) developed a TBI databank for German-speaking countries.METHODS: From 2016 to 2020, the TBI databank DGNC/DGU was implemented as a module of the TraumaRegister (TR) DGU and tested in a 15-month pilot phase. Since its official launch in 2021, patients from the TR-DGU (intermediate or intensive care unit admission via shock room) with TBI (AIS head ≥ 1) can be enrolled. A data set of > 300 clinical, imaging, and laboratory variables, harmonized with other international TBI data collection structures is documented, and the treatment outcome is evaluated after 6- and 12 months.RESULTS: For this analysis, 318 patients in the TBI databank could be included (median age 58 years; 71% men). Falls were the most common cause of injury (55%), and antithrombotic medication was frequent (28%). Severe or moderate TBI were only present in 55% of patients, while 45% suffered a mild injury. Nevertheless, intracranial pathologies were present in 95% of brain imaging with traumatic subarachnoid hemorrhages (76%) being the most common. Intracranial surgeries were performed in 42% of cases. In-hospital mortality after TBI was 21% and surviving patients could be discharged after a median hospital stay of 11 days. At the 6-and 12 months follow-up, a favorable outcome was achieved by 70% and 90% of the participating TBI patients, respectively. Compared to a European cohort of 2138 TBI patients treated in the ICU between 2014 and 2017, patients in the TBI databank were already older, frailer, fell more commonly at home.CONCLUSION: Within five years, the TBI databank DGNC/DGU of the TR-DGU could be established and is since then prospectively enrolling TBI patients in German-speaking countries. With its large and harmonized data set and a 12-month follow-up, the TBI databank is a unique project in Europe, already allowing comparisons to other data collection structures and indicating a demographic change towards older and frailer TBI patients in Germany.

KW - Male

KW - Humans

KW - Middle Aged

KW - Female

KW - Registries

KW - Brain Injuries, Traumatic/diagnostic imaging

KW - Treatment Outcome

KW - Brain Injuries

KW - Germany/epidemiology

U2 - 10.1007/s00068-023-02260-6

DO - 10.1007/s00068-023-02260-6

M3 - SCORING: Journal article

C2 - 37022377

VL - 49

SP - 1171

EP - 1181

JO - EUR J TRAUMA EMERG S

JF - EUR J TRAUMA EMERG S

SN - 1863-9933

IS - 3

ER -