Delayed-enhancement magnetic resonance imaging in patients with clinically suspected stress cardiomyopathy (Tako-tsubo)

TY - JOUR

T1 - Delayed-enhancement magnetic resonance imaging in patients with clinically suspected stress cardiomyopathy (Tako-tsubo)

AU - Muellerleile, K

AU - Lund, G

AU - Groth, M

AU - Barmeyer, A

AU - Sultan, A

AU - Heitzer, T

AU - Willems, S

AU - Adam, G

AU - Meinertz, T

AU - Koester, R

N1 - (c) Georg Thieme Verlag KG Stuttgart-New York.

PY - 2010/1

Y1 - 2010/1

N2 - PURPOSE: To compare the ability of delayed-enhancement magnetic resonance imaging (DE-MRI) and other MRI and clinical parameters to identify diseases mimicking stress cardiomyopathy (SCM).MATERIALS AND METHODS: The study included 14 consecutive patients fulfilling the American Heart Association (AHA) criteria for SCM with acute left ventricular dysfunction in the absence of coronary artery disease, triggered by psychological stress. The MRI protocol consisted of cine, T 2-weighted, first-pass-perfusion (FPP) and DE-MRI.RESULTS: Six patients with DE were classified as mimicking SCM (non-SCM) and 8 patients without DE as SCM. FPP defects were found in 4 patients with non-SCM and in none with SCM (p < 0.05). Myocardial edema was found in 5 patients with non-SCM and in 2 patients with SCM (p = ns). No significant differences in clinical findings such as ECG, cardiac markers and echocardiographic recovery of left ventricular function were found between patients with non-SCM and SCM.CONCLUSION: Non-SCM defined by DE-MRI is a frequent finding in patients fulfilling the AHA criteria for SCM. Clinical findings seem to be of limited value to differentiate between non-SCM and SCM.

AB - PURPOSE: To compare the ability of delayed-enhancement magnetic resonance imaging (DE-MRI) and other MRI and clinical parameters to identify diseases mimicking stress cardiomyopathy (SCM).MATERIALS AND METHODS: The study included 14 consecutive patients fulfilling the American Heart Association (AHA) criteria for SCM with acute left ventricular dysfunction in the absence of coronary artery disease, triggered by psychological stress. The MRI protocol consisted of cine, T 2-weighted, first-pass-perfusion (FPP) and DE-MRI.RESULTS: Six patients with DE were classified as mimicking SCM (non-SCM) and 8 patients without DE as SCM. FPP defects were found in 4 patients with non-SCM and in none with SCM (p < 0.05). Myocardial edema was found in 5 patients with non-SCM and in 2 patients with SCM (p = ns). No significant differences in clinical findings such as ECG, cardiac markers and echocardiographic recovery of left ventricular function were found between patients with non-SCM and SCM.CONCLUSION: Non-SCM defined by DE-MRI is a frequent finding in patients fulfilling the AHA criteria for SCM. Clinical findings seem to be of limited value to differentiate between non-SCM and SCM.

KW - Aged

KW - Contrast Media/administration & dosage

KW - Diagnosis, Differential

KW - Female

KW - Humans

KW - Image Enhancement/methods

KW - Image Processing, Computer-Assisted/methods

KW - Imaging, Three-Dimensional/methods

KW - Magnetic Resonance Imaging/methods

KW - Magnetic Resonance Imaging, Cine/methods

KW - Male

KW - Middle Aged

KW - Myocardial Contraction/physiology

KW - Retrospective Studies

KW - Sensitivity and Specificity

KW - Stress, Psychological/complications

KW - Stroke Volume/physiology

KW - Takotsubo Cardiomyopathy/diagnosis

KW - Ventricular Dysfunction, Left/diagnosis

U2 - 10.1055/s-0028-1109617

DO - 10.1055/s-0028-1109617

M3 - SCORING: Journal article

C2 - 19676014

VL - 182

SP - 29

EP - 35

JO - ROFO-FORTSCHR RONTG

JF - ROFO-FORTSCHR RONTG

SN - 1438-9029

IS - 1

ER -