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Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders.

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Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders. / Schennach-Wolff, Rebecca; Jäger, Markus; Seemüller, Florian; Obermeier, Michael; Messer, Thomas; Laux, Gerd; Pfeiffer, Herbert; Naber, Dieter; Schmidt, Lutz G; Gaebel, Wolfgang; Huff, Wolfgang; Heuser, Isabella; Maier, Wolfgang; Lemke, Matthias R; Rüther, Eckart; Buchkremer, Gerd; Gastpar, Markus; Möller, Hans-Jürgen; Riedel, Michael.

In: SCHIZOPHR RES, 2009.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schennach-Wolff, R, Jäger, M, Seemüller, F, Obermeier, M, Messer, T, Laux, G, Pfeiffer, H, Naber, D, Schmidt, LG, Gaebel, W, Huff, W, Heuser, I, Maier, W, Lemke, MR, Rüther, E, Buchkremer, G, Gastpar, M, Möller, H-J & Riedel, M 2009, 'Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders.', SCHIZOPHR RES. <http://www.ncbi.nlm.nih.gov/pubmed/19560901?dopt=Citation>

APA

Schennach-Wolff, R., Jäger, M., Seemüller, F., Obermeier, M., Messer, T., Laux, G., Pfeiffer, H., Naber, D., Schmidt, L. G., Gaebel, W., Huff, W., Heuser, I., Maier, W., Lemke, M. R., Rüther, E., Buchkremer, G., Gastpar, M., Möller, H-J., & Riedel, M. (2009). Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders. SCHIZOPHR RES. http://www.ncbi.nlm.nih.gov/pubmed/19560901?dopt=Citation

Vancouver

Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Messer T, Laux G et al. Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders. SCHIZOPHR RES. 2009.

Bibtex

@article{fdba642ea688432eb18a2aa1f2049787,
title = "Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders.",
abstract = "BACKGROUND: To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group. METHOD: PANSS ratings were used to evaluate the symptomatic treatment outcome of 262 inpatients with schizophrenia spectrum disorders within a naturalistic multicenter trial. Functional remission was defined as a GAF score >61 (Global Assessment of Functioning Scale), SOFAS score >61 (Social and Occupational Functioning Scale) and a SF-36 mental health subscore >40 (Medical Outcomes Study-Short Form Health Survey). Multivariate logistic regression and CART analyses were used to determine valid clinical and sociodemographic predictors. RESULTS: In total, 52 patients (20%) fulfilled the criteria for functional remission, 125 patients (48%) achieved symptomatic resolution and when criteria for functional remission and symptomatic resolution were combined 33 patients (13%) achieved complete remission. Younger age, employment, a shorter duration of illness, a shorter length of current episode, less suicidality, and a lower PANSS negative and global subscore at admission were predictive of functional remission. The regression model showed a predictive value of more than 80%. CONCLUSIONS: A significant association was found between functional remission and symptomatic resolution, indicating reasonable validity of the proposed definition for functional outcome. The revealed predictors for functional treatment outcome emphasize the need for psychosocial and vocational rehabilitation in schizophrenic patients.",
author = "Rebecca Schennach-Wolff and Markus J{\"a}ger and Florian Seem{\"u}ller and Michael Obermeier and Thomas Messer and Gerd Laux and Herbert Pfeiffer and Dieter Naber and Schmidt, {Lutz G} and Wolfgang Gaebel and Wolfgang Huff and Isabella Heuser and Wolfgang Maier and Lemke, {Matthias R} and Eckart R{\"u}ther and Gerd Buchkremer and Markus Gastpar and Hans-J{\"u}rgen M{\"o}ller and Michael Riedel",
year = "2009",
language = "Deutsch",
journal = "SCHIZOPHR RES",
issn = "0920-9964",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders.

AU - Schennach-Wolff, Rebecca

AU - Jäger, Markus

AU - Seemüller, Florian

AU - Obermeier, Michael

AU - Messer, Thomas

AU - Laux, Gerd

AU - Pfeiffer, Herbert

AU - Naber, Dieter

AU - Schmidt, Lutz G

AU - Gaebel, Wolfgang

AU - Huff, Wolfgang

AU - Heuser, Isabella

AU - Maier, Wolfgang

AU - Lemke, Matthias R

AU - Rüther, Eckart

AU - Buchkremer, Gerd

AU - Gastpar, Markus

AU - Möller, Hans-Jürgen

AU - Riedel, Michael

PY - 2009

Y1 - 2009

N2 - BACKGROUND: To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group. METHOD: PANSS ratings were used to evaluate the symptomatic treatment outcome of 262 inpatients with schizophrenia spectrum disorders within a naturalistic multicenter trial. Functional remission was defined as a GAF score >61 (Global Assessment of Functioning Scale), SOFAS score >61 (Social and Occupational Functioning Scale) and a SF-36 mental health subscore >40 (Medical Outcomes Study-Short Form Health Survey). Multivariate logistic regression and CART analyses were used to determine valid clinical and sociodemographic predictors. RESULTS: In total, 52 patients (20%) fulfilled the criteria for functional remission, 125 patients (48%) achieved symptomatic resolution and when criteria for functional remission and symptomatic resolution were combined 33 patients (13%) achieved complete remission. Younger age, employment, a shorter duration of illness, a shorter length of current episode, less suicidality, and a lower PANSS negative and global subscore at admission were predictive of functional remission. The regression model showed a predictive value of more than 80%. CONCLUSIONS: A significant association was found between functional remission and symptomatic resolution, indicating reasonable validity of the proposed definition for functional outcome. The revealed predictors for functional treatment outcome emphasize the need for psychosocial and vocational rehabilitation in schizophrenic patients.

AB - BACKGROUND: To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group. METHOD: PANSS ratings were used to evaluate the symptomatic treatment outcome of 262 inpatients with schizophrenia spectrum disorders within a naturalistic multicenter trial. Functional remission was defined as a GAF score >61 (Global Assessment of Functioning Scale), SOFAS score >61 (Social and Occupational Functioning Scale) and a SF-36 mental health subscore >40 (Medical Outcomes Study-Short Form Health Survey). Multivariate logistic regression and CART analyses were used to determine valid clinical and sociodemographic predictors. RESULTS: In total, 52 patients (20%) fulfilled the criteria for functional remission, 125 patients (48%) achieved symptomatic resolution and when criteria for functional remission and symptomatic resolution were combined 33 patients (13%) achieved complete remission. Younger age, employment, a shorter duration of illness, a shorter length of current episode, less suicidality, and a lower PANSS negative and global subscore at admission were predictive of functional remission. The regression model showed a predictive value of more than 80%. CONCLUSIONS: A significant association was found between functional remission and symptomatic resolution, indicating reasonable validity of the proposed definition for functional outcome. The revealed predictors for functional treatment outcome emphasize the need for psychosocial and vocational rehabilitation in schizophrenic patients.

M3 - SCORING: Zeitschriftenaufsatz

JO - SCHIZOPHR RES

JF - SCHIZOPHR RES

SN - 0920-9964

ER -