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Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI

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Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI. / Karch, Susanne; Voelker, Julia Madeleine; Thalmeier, Tobias; Ertl, Matthias; Leicht, Gregor; Pogarell, Oliver; Mulert, Christoph.

In: FRONT PSYCHIATRY, Vol. 5, 22.04.2014, p. 41.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Karch, S, Voelker, JM, Thalmeier, T, Ertl, M, Leicht, G, Pogarell, O & Mulert, C 2014, 'Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI', FRONT PSYCHIATRY, vol. 5, pp. 41. https://doi.org/10.3389/fpsyt.2014.00041

APA

Karch, S., Voelker, J. M., Thalmeier, T., Ertl, M., Leicht, G., Pogarell, O., & Mulert, C. (2014). Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI. FRONT PSYCHIATRY, 5, 41. https://doi.org/10.3389/fpsyt.2014.00041

Vancouver

Karch S, Voelker JM, Thalmeier T, Ertl M, Leicht G, Pogarell O et al. Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI. FRONT PSYCHIATRY. 2014 Apr 22;5:41. https://doi.org/10.3389/fpsyt.2014.00041

Bibtex

@article{9f77ac181ec445179d1dc0942080830d,
title = "Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI",
abstract = "Deficits in executive functions, including voluntary decisions are among the core symptoms of attention deficit/hyperactivity disorder (ADHD) patients. In order to clarify the spatiotemporal characteristics of these deficits, a simultaneous EEG/functional MRI (fMRI) study was performed. Single-trial coupling was used to integrate temporal EEG information in the fMRI analyses and to correlate the trial by trial variation in the different event-related potential amplitudes with fMRI BOLD responses. The results demonstrated that during voluntary selection early electrophysiological responses (N2) were associated with responses in similar brain regions in healthy participants as well as in ADHD patients, e.g., in the medial-frontal cortex and the inferior parietal gyrus. However, ADHD patients presented significantly reduced N2-related BOLD responses compared to healthy controls especially in frontal areas. These results support the hypothesis that in ADHD patients executive deficits are accompanied by early dysfunctions, especially in frontal brain areas.",
author = "Susanne Karch and Voelker, {Julia Madeleine} and Tobias Thalmeier and Matthias Ertl and Gregor Leicht and Oliver Pogarell and Christoph Mulert",
year = "2014",
month = apr,
day = "22",
doi = "10.3389/fpsyt.2014.00041",
language = "English",
volume = "5",
pages = "41",
journal = "FRONT PSYCHIATRY",
issn = "1664-0640",
publisher = "Frontiers Research Foundation",

}

RIS

TY - JOUR

T1 - Deficits during Voluntary Selection in Adult Patients with ADHD: New Insights from Single-Trial Coupling of Simultaneous EEG/fMRI

AU - Karch, Susanne

AU - Voelker, Julia Madeleine

AU - Thalmeier, Tobias

AU - Ertl, Matthias

AU - Leicht, Gregor

AU - Pogarell, Oliver

AU - Mulert, Christoph

PY - 2014/4/22

Y1 - 2014/4/22

N2 - Deficits in executive functions, including voluntary decisions are among the core symptoms of attention deficit/hyperactivity disorder (ADHD) patients. In order to clarify the spatiotemporal characteristics of these deficits, a simultaneous EEG/functional MRI (fMRI) study was performed. Single-trial coupling was used to integrate temporal EEG information in the fMRI analyses and to correlate the trial by trial variation in the different event-related potential amplitudes with fMRI BOLD responses. The results demonstrated that during voluntary selection early electrophysiological responses (N2) were associated with responses in similar brain regions in healthy participants as well as in ADHD patients, e.g., in the medial-frontal cortex and the inferior parietal gyrus. However, ADHD patients presented significantly reduced N2-related BOLD responses compared to healthy controls especially in frontal areas. These results support the hypothesis that in ADHD patients executive deficits are accompanied by early dysfunctions, especially in frontal brain areas.

AB - Deficits in executive functions, including voluntary decisions are among the core symptoms of attention deficit/hyperactivity disorder (ADHD) patients. In order to clarify the spatiotemporal characteristics of these deficits, a simultaneous EEG/functional MRI (fMRI) study was performed. Single-trial coupling was used to integrate temporal EEG information in the fMRI analyses and to correlate the trial by trial variation in the different event-related potential amplitudes with fMRI BOLD responses. The results demonstrated that during voluntary selection early electrophysiological responses (N2) were associated with responses in similar brain regions in healthy participants as well as in ADHD patients, e.g., in the medial-frontal cortex and the inferior parietal gyrus. However, ADHD patients presented significantly reduced N2-related BOLD responses compared to healthy controls especially in frontal areas. These results support the hypothesis that in ADHD patients executive deficits are accompanied by early dysfunctions, especially in frontal brain areas.

U2 - 10.3389/fpsyt.2014.00041

DO - 10.3389/fpsyt.2014.00041

M3 - SCORING: Journal article

C2 - 24795657

VL - 5

SP - 41

JO - FRONT PSYCHIATRY

JF - FRONT PSYCHIATRY

SN - 1664-0640

ER -