Deep brain stimulation to reduce sexual drive

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Deep brain stimulation to reduce sexual drive. / Fuß, Johannes; Auer, Matthias K. ; Biedermann, Sarah; Briken, Peer; Hacke, Werner.

In: J PSYCHIATR NEUROSCI, Vol. 40, No. 6, 2015, p. 429–431.

Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

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@article{64d59323a8264b26a7418d33d323248b,
title = "Deep brain stimulation to reduce sexual drive",
abstract = "To date there are few treatment options to reduce high sexual drive or sexual urges in paraphilic patients with a risk for sexual offending. Pharmacological therapy aims to reduce sexual drive by lowering testosterone at the cost of severe side effects. We hypothesize that high sexual drive could also be reduced with deep brain stimulation (DBS) of circuits that generate sexual drive. This approach would help to avoid systemic side effects of antiandrogenic drug therapies. So far the best investigated target to reduce sexual drive is the ventromedial hypothalamus, which was lesioned unilaterally and bilaterally by stereotaxic interventions in paraphilic patients in the 1970s. Here, we discuss DBS as a treatment strategy in patients with severe paraphilic disorders with a serious risk of sexual offending. There are profound ethical and practical issues associated with DBS treatment of paraphilic patients that must be solved before considering such a treatment approach.",
author = "Johannes Fu{\ss} and Auer, {Matthias K.} and Sarah Biedermann and Peer Briken and Werner Hacke",
note = "Document Type:Editorial Material",
year = "2015",
doi = "10.1503/jpn.150003",
language = "English",
volume = "40",
pages = "429–431",
journal = "J PSYCHIATR NEUROSCI",
issn = "1180-4882",
publisher = "Canadian Medical Association",
number = "6",

}

RIS

TY - JOUR

T1 - Deep brain stimulation to reduce sexual drive

AU - Fuß, Johannes

AU - Auer, Matthias K.

AU - Biedermann, Sarah

AU - Briken, Peer

AU - Hacke, Werner

N1 - Document Type:Editorial Material

PY - 2015

Y1 - 2015

N2 - To date there are few treatment options to reduce high sexual drive or sexual urges in paraphilic patients with a risk for sexual offending. Pharmacological therapy aims to reduce sexual drive by lowering testosterone at the cost of severe side effects. We hypothesize that high sexual drive could also be reduced with deep brain stimulation (DBS) of circuits that generate sexual drive. This approach would help to avoid systemic side effects of antiandrogenic drug therapies. So far the best investigated target to reduce sexual drive is the ventromedial hypothalamus, which was lesioned unilaterally and bilaterally by stereotaxic interventions in paraphilic patients in the 1970s. Here, we discuss DBS as a treatment strategy in patients with severe paraphilic disorders with a serious risk of sexual offending. There are profound ethical and practical issues associated with DBS treatment of paraphilic patients that must be solved before considering such a treatment approach.

AB - To date there are few treatment options to reduce high sexual drive or sexual urges in paraphilic patients with a risk for sexual offending. Pharmacological therapy aims to reduce sexual drive by lowering testosterone at the cost of severe side effects. We hypothesize that high sexual drive could also be reduced with deep brain stimulation (DBS) of circuits that generate sexual drive. This approach would help to avoid systemic side effects of antiandrogenic drug therapies. So far the best investigated target to reduce sexual drive is the ventromedial hypothalamus, which was lesioned unilaterally and bilaterally by stereotaxic interventions in paraphilic patients in the 1970s. Here, we discuss DBS as a treatment strategy in patients with severe paraphilic disorders with a serious risk of sexual offending. There are profound ethical and practical issues associated with DBS treatment of paraphilic patients that must be solved before considering such a treatment approach.

U2 - 10.1503/jpn.150003

DO - 10.1503/jpn.150003

M3 - Other (editorial matter etc.)

VL - 40

SP - 429

EP - 431

JO - J PSYCHIATR NEUROSCI

JF - J PSYCHIATR NEUROSCI

SN - 1180-4882

IS - 6

ER -