Deep brain stimulation of the subthalamic nucleus improves cognitive flexibility but impairs response inhibition in Parkinson disease.

  • Karsten Witt
  • Ulrich Pulkowski
  • Jan Herzog
  • Delia Lorenz
  • Wolfgang Hamel
  • Günther Deuschl
  • Paul Krack

Related Research units

Abstract

Deep brain stimulation of the subthalamic nucleus (STN) improves motor symptoms of Parkinson disease. Although several studies have assessed cognitive functions before surgery and after long-term STN stimulation, only a few have assessed patients while stimulation is on and off to more specifically address the short-term cognitive effects of STN deep brain stimulation.

Bibliographical data

Original languageGerman
Article number5
ISSN0003-9942
Publication statusPublished - 2004
pubmed 15148146