Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®)
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Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®). / Edler, Carolin; Klein, Anke; Schröder, Ann Sophie; Sperhake, Jan-Peter; Ondruschka, Benjamin.
In: LEGAL MED-TOKYO, Vol. 51, 101895, 07.2021, p. 101895.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®)
AU - Edler, Carolin
AU - Klein, Anke
AU - Schröder, Ann Sophie
AU - Sperhake, Jan-Peter
AU - Ondruschka, Benjamin
N1 - Copyright © 2021 Elsevier B.V. All rights reserved.
PY - 2021/7
Y1 - 2021/7
N2 - Since 27th December 2020, a mRNA vaccine from BioNTech / Pfizer (Comirnaty®) has been used across Germany. As of 12th March 2021, 286 fatalities of vaccinated German individuals were registered at the Paul-Ehrlich-Institute with time intervals after vaccination between one hour to 40 days. From our catchment area in northern Germany, we have so far become aware of 22 deaths in connection with vaccination in a 5 week period (range: 0–28 days after vaccination). Three death cases after vaccination with Comirnaty®, which were autopsied at the Institute of Legal Medicine Hamburg, are presented in more detail. All three deceased had severe cardiovascular diseases, among other comorbidities, and died in the context of these pre-existing conditions, while one case developed a COVID-19 pneumonia as cause of death. Taking into account the results of the postmortem examination a causal relation between the vaccination and the death was not established in any case. If there are indications of an allergic reaction, histological and postmortem laboratory examinations should be performed subsequent to the autopsy (tryptase, total IgE, CRP, interleukin-6, complement activity C3/C5).
AB - Since 27th December 2020, a mRNA vaccine from BioNTech / Pfizer (Comirnaty®) has been used across Germany. As of 12th March 2021, 286 fatalities of vaccinated German individuals were registered at the Paul-Ehrlich-Institute with time intervals after vaccination between one hour to 40 days. From our catchment area in northern Germany, we have so far become aware of 22 deaths in connection with vaccination in a 5 week period (range: 0–28 days after vaccination). Three death cases after vaccination with Comirnaty®, which were autopsied at the Institute of Legal Medicine Hamburg, are presented in more detail. All three deceased had severe cardiovascular diseases, among other comorbidities, and died in the context of these pre-existing conditions, while one case developed a COVID-19 pneumonia as cause of death. Taking into account the results of the postmortem examination a causal relation between the vaccination and the death was not established in any case. If there are indications of an allergic reaction, histological and postmortem laboratory examinations should be performed subsequent to the autopsy (tryptase, total IgE, CRP, interleukin-6, complement activity C3/C5).
KW - Aged
KW - Aged, 80 and over
KW - Autopsy
KW - COVID-19 Vaccines
KW - Cause of Death
KW - Fatal Outcome
KW - Female
KW - Frail Elderly
KW - Germany/epidemiology
KW - Humans
KW - Male
KW - Multimorbidity
KW - Myocardial Infarction/diagnosis
KW - Pneumonia/diagnosis
KW - Pulmonary Embolism/diagnosis
KW - Vaccines, Synthetic
U2 - 10.1016/j.legalmed.2021.101895
DO - 10.1016/j.legalmed.2021.101895
M3 - SCORING: Journal article
C2 - 33895650
VL - 51
SP - 101895
JO - LEGAL MED-TOKYO
JF - LEGAL MED-TOKYO
SN - 1344-6223
M1 - 101895
ER -