D-amphetamine does not improve outcome of somatosensory training
Abstract
BACKGROUND: D-amphetamine has been shown to affect early stages of stroke recovery, and may have a beneficial effect on functions when administered later after stroke.
OBJECTIVE: To test D-amphetamine effects on skill acquisition after the acute or subacute stages of stroke, when lesion-related structural changes have consolidated.
METHODS: Sixteen healthy subjects were treated with D-amphetamine during a 4-week training of tactile frequency discrimination in a placebo-controlled, double-blind design.
RESULTS: All subjects improved significantly in tactile temporal acuity. However, improvement did not differ in subjects treated with or without D-amphetamine.
CONCLUSION: No beneficial effect of D-amphetamine on somatosensory training improvements was found in healthy subjects.
Bibliographical data
Original language | English |
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ISSN | 0028-3878 |
Publication status | Published - 26.12.2001 |
Externally published | Yes |
PubMed | 11756605 |
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