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Cytokines in Inflammatory Disease

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Cytokines in Inflammatory Disease. / Kany, Shinwan; Vollrath, Jan Tilmann; Relja, Borna.

In: INT J MOL SCI, Vol. 20, No. 23, 28.11.2019.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Kany, S, Vollrath, JT & Relja, B 2019, 'Cytokines in Inflammatory Disease', INT J MOL SCI, vol. 20, no. 23. https://doi.org/10.3390/ijms20236008

APA

Kany, S., Vollrath, J. T., & Relja, B. (2019). Cytokines in Inflammatory Disease. INT J MOL SCI, 20(23). https://doi.org/10.3390/ijms20236008

Vancouver

Kany S, Vollrath JT, Relja B. Cytokines in Inflammatory Disease. INT J MOL SCI. 2019 Nov 28;20(23). https://doi.org/10.3390/ijms20236008

Bibtex

@article{9d7596ec4a10437586bae0c983d9a170,
title = "Cytokines in Inflammatory Disease",
abstract = "This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this review, we focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of inflammatory impacts (e.g., shock, trauma, immune dysregulation, osteoporosis, and/or critical illness).",
keywords = "Animals, Cytokines/genetics, Humans, Lymphocytes/immunology, Monocytes/immunology, Neutrophils/immunology, Systemic Inflammatory Response Syndrome/blood",
author = "Shinwan Kany and Vollrath, {Jan Tilmann} and Borna Relja",
year = "2019",
month = nov,
day = "28",
doi = "10.3390/ijms20236008",
language = "English",
volume = "20",
journal = "INT J MOL SCI",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "23",

}

RIS

TY - JOUR

T1 - Cytokines in Inflammatory Disease

AU - Kany, Shinwan

AU - Vollrath, Jan Tilmann

AU - Relja, Borna

PY - 2019/11/28

Y1 - 2019/11/28

N2 - This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this review, we focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of inflammatory impacts (e.g., shock, trauma, immune dysregulation, osteoporosis, and/or critical illness).

AB - This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this review, we focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of inflammatory impacts (e.g., shock, trauma, immune dysregulation, osteoporosis, and/or critical illness).

KW - Animals

KW - Cytokines/genetics

KW - Humans

KW - Lymphocytes/immunology

KW - Monocytes/immunology

KW - Neutrophils/immunology

KW - Systemic Inflammatory Response Syndrome/blood

U2 - 10.3390/ijms20236008

DO - 10.3390/ijms20236008

M3 - SCORING: Review article

C2 - 31795299

VL - 20

JO - INT J MOL SCI

JF - INT J MOL SCI

SN - 1661-6596

IS - 23

ER -